Rhesus HSP60 cDNA Clone

Sino Biological Inc. — Biological Solution Specialist

Protein, Antibody, ELISA Kit, cDNA Clone – All Produced in House

Sino Biological is the new leader in life science research tool developer worldwide. All our proteins are manufactured in bulk quantities using sequence verified vectors and state-of-the-art mammalian, insect, or E. coli expression processes. All reagents are available in both small retails and bulk packages - both offering 30-80% cost saving compared to currently leading brands. We installed the same quality requirement and assurance for preclinical products to reagent products, hence the quality of Sino Biological products is typically higher than that of other reagent providers.

Rhesus HSP60 cDNA Clone Products

All HSP60 Products list

• HSP60 cDNA Clone

  – Rhesus HSP60 cDNA Clone

Browse HSP60 cDNA Clone Products by Following Categories

HSP60 Protein , Antibody, ELISA Kit, cDNA Clone

• HSP60 cDNA Clone

  – Human HSP60 cDNA Clone

  – Mouse HSP60 cDNA Clone

  – Rat HSP60 cDNA Clone

  – Rhesus HSP60 cDNA Clone

  – Cynomolgus HSP60 cDNA Clone

  – Canine (Dog) HSP60 cDNA Clone

  – Ferret HSP60 cDNA Clone

  – Bovine HSP60 cDNA Clone

Additional HSP60 Products

• HSP60 Protein

• HSP60 Antibody

• HSP60 ELISA Kit

Summary for HSP60

HSP60, also known as HSPD1, is a member of the chaperonin family. HSP60 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. It may also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. HSP60 gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.Defects in HSP60 are a cause of spastic paraplegia autosomal dominant type 13 (SPG13). Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Defects in HSP60 are the cause of leukodystrophy hypomyelinating type 4 (HLD4); also called mitochondrial HSP60 chaperonopathy or MitCHAP-60 disease. HLD4 is a severe autosomal recessive hypomyelinating leukodystrophy. HSP60 is cinically characterized by infantile-onset rotary nystagmus, progressive spastic paraplegia, neurologic regression, motor impairment, profound mental retardation. Death usually occurrs within the first two decades of life.

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