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Renin / REN / Angiotensinogenase Antibody, Rabbit MAb

  • Renin / REN / Angiotensinogenase Antibody, Rabbit MAb, Immunohistochemistry
  • Renin / REN / Angiotensinogenase Antibody, Rabbit MAb, Western blot
  • Renin / REN / Angiotensinogenase Antibody, Rabbit MAb, Immunofluorescence
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Human RENIN Antibody Product Information
Immunogen:Recombinant Human Renin protein (Catalog#10969-H08H)
Clone ID:009
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human Renin (rh Renin; Catalog#10969-H08H; NP_000528.1; Met 1-Arg 406).
Human RENIN Antibody WB Application Image
Human RENIN Antibody IHC Application Image
Renin / REN / Angiotensinogenase Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human RENIN in human kidney with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Human RENIN Antibody IF Application Image
Renin / REN / Angiotensinogenase Antibody, Rabbit MAb, Immunofluorescence
[Click to enlarge image]
Caption:
Immunofluorescence staining of Human Renin in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human Renin monoclonal antibody (15 µg/ml) at 37℃ 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
Other RENIN Antibody Products
Immunochemical staining of human CCNF in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Renin Background

Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression.

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