After search, choose a molecule or a kind of categories listed in the left to narrow down your filter. If you have any problems, please contact us!
Text Size:AAA

REN1 / Renin-1 Antibody, Rabbit MAb

DatasheetReviewsRelated ProductsProtocols
Mouse RENIN Antibody Product Information
Immunogen:Recombinant Mouse REN1 protein (Catalog#50279-M08H)
Clone ID:1
Ig Type:Rabbit IgG
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse REN1 (rM REN1; Catalog#50279-M08H; NP_112469.1; Met 1-Arg 402).
Mouse RENIN Antibody Usage Guide
Specificity:Mouse REN1 / Renin-1
No cross-reactivity with in ELISA
Mouse Cathepsin D / CTSD
Application:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse REN1. The detection limit for Mouse REN1 is approximately 0.0049 ng/well.

IHC-P: 2-15 μg/mL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse RENIN Antibody IHC Application Image
REN1 / Renin-1 Antibody, Rabbit MAb, Immunohistochemistry
[Click to enlarge image]
Immunochemical staining of mouse REN1 in mouse kidney with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to juxtaglomerular cell. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
Other RENIN Antibody Products
Renin Background

Mouse Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression.

Product nameProduct name
Size / Price
Catalog: 50279-R001-50
List Price: 
Price:      (You Save: )
50 µg
100 µg
AvailabilityIn Stock
Bulk Discount InquiryAdd to Cart
All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.