|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Rat KLK13 ORF mammalian expression plasmid, C-GFPSpark tag||RG80544-ACG|
|Rat KLK13 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||RG80544-ACR|
|Rat KLK13 ORF mammalian expression plasmid, C-Flag tag||RG80544-CF|
|Rat KLK13 ORF mammalian expression plasmid, C-His tag||RG80544-CH|
|Rat KLK13 ORF mammalian expression plasmid, C-Myc tag||RG80544-CM|
|Rat KLK13 ORF mammalian expression plasmid, C-HA tag||RG80544-CY|
|Rat KLK13 ORF mammalian expression plasmid, N-Flag tag||RG80544-NF|
|Rat KLK13 ORF mammalian expression plasmid, N-His tag||RG80544-NH|
|Rat KLK13 ORF mammalian expression plasmid, N-Myc tag||RG80544-NM|
|Rat KLK13 ORF mammalian expression plasmid, N-HA tag||RG80544-NY|
|Rat KLK13 Gene cDNA clone plasmid||RG80544-U|
|Rat KLK13 natural ORF mammalian expression plasmid||RG80544-UT|
|Learn more about expression Vectors|
Human tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.