All RHEB reagents are produced in house and quality controlled, including 40 RHEB Gene, 1 RHEB Lysate, 1 RHEB Protein, 1 RHEB qPCR. All RHEB reagents are ready to use.
Recombinant RHEB proteins are expressed by Baculovirus-Insect Cells with fusion tags as N-His.
RHEBcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each RHEB of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
RHEB is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins. RHEB gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is vital in regulation of growth and cell cycle progression due to its role in the insulin / TOR / S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of RHEB is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.