- EGFR Signaling Pathway
- TGF-beta Signaling
- Canonical Wnt Signaling
- non-Canonical Wnt Signaling
- Notch Signaling
- p53 Pathway
- NF-kB Pathway
- Cytokine Signaling
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RELT / TNFRSF19L Antibody Datasheet
|Order or Inquire for RELT / TNFRSF19L Antibody product||Quality antibodies||Antibody production services|
|Detection limit is 0.00975 ng/well in ELISA|
RELT / TNFRSF19L Antibody Product Information
Recombinant Human RELT / TNFRSF19L protein (Catalog#10530-H08H)
|Antibody Type :||Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )|
Clone ID :
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.|
This antibody was obtained from a rabbit immunized with purified, recombinant Human RELT / TNFRSF19L (rh RELT / TNFRSF19L; Catalog#10530-H08H; NP_116260.2; Met 1-Ala 160).
RELT / TNFRSF19L Antibody Usage Guide
Human RELT / TNFRSF19L
|Direct ELISA :||This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human RELT. The detection limit for Human RELT is approximately 0.00975 ng/well.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
RELT / TNFRSF19L Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|RELT/TNFRSF19L||Human||RELT/TNFRSF19L/Fc Protein, Recombinant||10530-H03H|
|RELT/TNFRSF19L||Human||RELT/TNFRSF19L Protein, Recombinant||10530-H08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|WB, ELISA||RELT/TNFRSF19L Antibody, Rabbit PAb||10530-RP01|
|WB, ELISA||RELT/TNFRSF19L Antibody, Rabbit PAb (Antigen Affinity Purified)||10530-RP02|
|ELISA||RELT / TNFRSF19L Antibody||10530-R135|
RELT / TNFRSF19L Antibody Background
Tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), also known as RELT (Receptor Expressed in Lymphoid Tissues), is a member of the TNF-receptor superfamily. Human RELT cDNA encodes a 430 aa precursor protein with a putative 26 aa signal peptide, a 136 aa extracellular domain containing one TNF receptor cysteine-rich domain and one potential N-linked glycosylation site, a 21 aa transmembrane domain and a 247 aa cytoplasmic region containing no death domain. Among TNFRSF members, the RELT extracellular domain is most closely related to that of TNFRSF19 and OX40. This receptor is especially abundant in hematologic tissues such as spleen, lymph node, and peripheral blood leukocytes as well as in leukemias and lymphomas. RELT has been shown to exclusively bind the adaptor protein TNF receptor-associated factor 1 (TRAF1). It also activates the NF-kappaB pathway and is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Human RELT shares 85% and 96% aa sequence homology with mouse and macaque RELT, respectively.
- Sica, G.L. et al., 2001, Blood. 97: 2702-7.
- Strausberg,RL.et al.,2003, Proc.Natl.Acad.Sci.USA. 99 (26): 16899-903.
- Polek,TC. et al.,2006, Biochem.Biophys.Res.Commun. 349 (3): 1016-24.
- Bossen C, et al., 2006, J. Biol. Chem. 281 (20): 13964-13971.
- Cusick, JK. et al., 2006, Biochem. Biophys.Res.Commun. 340 (2): 535-43.
|Tumor Necrosis Factor (TNF) Family & Receptor|