All NF-kB p65 reagents are produced in house and quality controlled, including 3 NF-kB p65 Antibody, 30 NF-kB p65 Gene, 1 NF-kB p65 Protein, 1 NF-kB p65 qPCR. All NF-kB p65 reagents are ready to use.
Recombinant NF-kB p65 proteins are expressed by E. coli with fusion tags as N-GST.
NF-kB p65antibodies are validated with different applications, which are ELISA, FCM, WB, ICC/IF, IF.
NF-kB p65cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each NF-kB p65 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth plate chondrocytes where it facilitates chondrogenesis. The v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) gene encodes the major component of the NF-?B complex. NF-kappaB is a generic name for an evolutionarily conserved transcription-factor system that contributes to the mounting of an effective immune response but is also involved in the regulation of cell proliferation, development, and apoptosis. The implication of NF-kappaB in central biological processes and its extraordinary connectivity to other signaling pathways raise a need for highly controlled regulation of NF-kappaB activity at several levels. The mammalian Rel/NF-kappaB family of transcription factors, including RelA, c-Rel, RelB, NF-kappaB1 (p50 and its precursor p105), and NF-kappaB2 (p52 and its precursor p100), plays a central role in the immune system by regulating several processes ranging from the development and survival of lymphocytes and lymphoid organs to the control of immune responses and malignant transformation.