Anti-REG3G Antibody

Cat: 11641-R002
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All REG3G Reagents
CRO Services
Product recommended

All REG3G Reagents
Anti-REG3G Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-REG3G Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human REG3G
Immunogen
Recombinant Human REG3G protein (Catalog#11641-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human REG3G (rh REG3G; Catalog#11641-H08H; NP_001008388.1; Met 1-Asp 175).
Source
Monoclonal Rabbit IgG Clone #002
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-REG3G Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-REG3G Antibody Alternative Names
Anti-LPPM429 Antibody;Anti-PAP-1B Antibody;Anti-PAP1B Antibody;Anti-PAPIB Antibody;Anti-REG-III Antibody;Anti-REGIII Antibody;Anti-UNQ429 Antibody
REG3G Background Information

Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on the primary structures of the encoded proteins of the genes, which are associated with tissue repair and have been directly implicated in pancreatic beta-cell regeneration. Reg proteins are expressed in various organs and are involved in cancers and neurodegenerative diseases. They display a typical C-type lectin-like domain but possess additional highly conserved amino acids. Regenerating islet-derived 3 gamma (REG3G), also known as pancreatitis-associated protein 1B (PAP1B), is a member of the secreted Reg superfamily and contains one typical C-type lectin domain. REG3G is expressed weakly in pancreas, strongly in intestinal tract, but not in hyperplastic islets REG3G might be a stress protein involved in the control of bacterial proliferation. It was indicated that REG3G specifically targets Gram-positive bacteria because it binds to their surface peptidoglycan layer, and serves as one of several antimicrobial peptides produced by paneth cells via stimulation of toll-like receptors (TLRs) by pathogen-associated molecular patterns (PAMPs).

Full Name
regenerating islet-derived 3 gamma
References
  • Narushima Y, et al. (1997) Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma. Gene. 185(2): 159-68.
  • Nata K, et al. (2004) Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III. Gene. 340(1): 161-70.
  • Laurine E, et al. (2005) PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication. Biochim Biophys Acta. 1727(3): 177-87.
  • Castellarin ML, et al. (2007) The identification and sequence analysis of a new Reg3gamma and Reg2 in the Syrian golden hamster. Biochim Biophys Acta. 1769(9-10): 579-85.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-REG3G Antibody Rabbit Polyclonal ELISA 11641-RP02
    Anti-REG3G Antibody Rabbit Polyclonal ELISA 11641-RP01
    info info
    添加购物车成功! 添加购物车失败!