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REG3A Protein & Antibody

Regenerating islet-derived 3 alpha

REG3A Products

REG3A Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
REG3A Human REG3A Protein, Recombinant 11235-H08H
REG3A Mouse REG3A Protein, Recombinant 50185-M08H
REG3A Rat REG3A Protein, Recombinant 80258-R02H
REG3A Rat REG3A Protein, Recombinant 80258-R08H

REG3A Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
REG3A
WB, ELISA REG3A Antibody, Rabbit PAb 11235-RP01
Human
REG3A
WB, ELISA REG3A Antibody, Rabbit PAb (Antigen Affinity Purified) 11235-RP02
Human
REG3A
WB, ELISA REG3A Antibody 11235-R019

REG3A cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
REG3A Human Homo sapiens REG3A cDNA Clone(NM_002580.1) HG11235-M
REG3A Mouse Mus musculus REG3A cDNA Clone MG50185-M
REG3A Rat REG3A cDNA Clone / ORF Clone RG80258-G

REG3A Alternative Names

REG3A, HIP, PAP, PAP-H, PAP1, PBCGF, REG-III, REG3 [Homo sapiens]

Reg3a, AV063448 [Mus musculus]

REG3A Related Areas

Immunology>>Adhesion Molecule>>Lectin>>REG3A

REG3A Related Products

Protein Products

Molecule Species Description //For Detailed Info. and Price------CLICK!
REG1A Human REG1A Protein, Recombinant
REG1B Human REG1B Protein, Recombinant
REG3D Mouse REG3D Protein, Recombinant
REG3G Human REG3G Protein, Recombinant
REG4 Human REG4 Protein, Recombinant
REG4 Mouse REG4 Protein, Recombinant

Antibody Products

Molecule Application Description //For Detailed Info. and Price------CLICK!
Human
REG1A
WB, ELISA Rabbit Polyclonal Antibody
Human
REG1A
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human
REG1B
WB, ELISA REG1B Antibody, Rabbit PAb
Human
REG1B
WB, ELISA REG1B Antibody, Rabbit PAb (Antigen Affinity Purified)
Human
REG3G
WB, ELISA REG3G Antibody, Rabbit MAb
Human
REG3G
WB, ELISA REG3G Antibody, Rabbit PAb
Human
REG3G
WB, ELISA REG3G Antibody, Rabbit PAb (Antigen Affinity Purified)
Human
REG4
WB, ELISA REG4 Antibody, Rabbit PAb
Human
REG4
WB, ELISA REG4 Antibody, Rabbit PAb (Antigen Affinity Purified)

cDNA Clone Products

Molecule Species Description //For Detailed Info. and Price------CLICK!
REG1A Human Homo sapiens REG1A cDNA Clone(NM_002909.4)
REG1B Human Homo sapiens REG1B cDNA Clone
REG3D Mouse Mus musculus REG3D cDNA Clone
REG3G Human Homo sapiens REG3G cDNA Clone
REG4 Human Homo sapiens REG4 cDNA Clone(NM_032044.2)
REG4 Mouse Mus musculus REG4 cDNA Clone

REG3A Background

Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis.

REG3A Related Studies

  1. Cavard C, et al. (2006) Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations. Oncogene. 25(4): 599-608.
  2. Choi B, et al. (2007) Downregulation of regenerating islet-derived 3 alpha (REG3A) in primary human gastric adenocarcinomas. Exp Mol Med. 39(6): 796-804.

 

 

REG3A related areas, pathways, and other information