REG1A Protein & Antibody

Regenerating islet-derived 1 alpha

REG1A Products

REG1A Protein, Recombinant

Molecule	Species	Description	Cat. No
REG1A	Human	REG1A Protein, Recombinant	11234-H08H

REG1A Antibody

Molecule	Application	Description	Cat. No
Human REG1A	WB, ELISA	Rabbit Polyclonal Antibody	11234-RP01
Human REG1A	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	11234-RP02
Human REG1A	WB, ELISA	Mouse Polyclonal Antibody	11234-MM02
Human REG1A	WB, ELISA	Mouse Polyclonal Antibody	11234-MM03

REG1A cDNA Clone

Molecule	Species	Description	Cat. No
REG1A	Human	Homo sapiens REG1A cDNA Clone(NM_002909.4)	HG11234-M
REG1A	Rat	REG1A cDNA Clone / ORF Clone	RG80300-G

REG1A Related Areas

Immunology>>Adhesion Molecule>>Lectin>>REG1A

REG1A Alternative Names

REG1A, ICRF, MGC12447, P19, PSP, PSPS, PSPS1, PTP, REG [Homo sapiens]

Reg1a, LITHOST, RATLITHOST, RATRGPI, RGPI, Reg, Reg1, Rgp1 [Mus musculus]

REG1A Related Products

Protein Products

Molecule	Species	Description
REG1B	Human	REG1B Protein, Recombinant
REG3A	Human	REG3A Protein, Recombinant
REG3A	Mouse	REG3A Protein, Recombinant
REG3D	Mouse	REG3D Protein, Recombinant
REG3G	Human	REG3G Protein, Recombinant
REG4	Human	REG4 Protein, Recombinant
REG4	Mouse	REG4 Protein, Recombinant

Antibody Products

Molecule	Application	Description
Human REG1B	WB, ELISA	REG1B Antibody, Rabbit PAb
Human REG1B	WB, ELISA	REG1B Antibody, Rabbit PAb (Antigen Affinity Purified)
Human REG3A	WB, ELISA	REG3A Antibody, Rabbit PAb
Human REG3A	WB, ELISA	REG3A Antibody, Rabbit PAb (Antigen Affinity Purified)
Human REG3G	WB, ELISA	REG3G Antibody, Rabbit MAb
Human REG3G	WB, ELISA	REG3G Antibody, Rabbit PAb
Human REG3G	WB, ELISA	REG3G Antibody, Rabbit PAb (Antigen Affinity Purified)
Human REG4	WB, ELISA	REG4 Antibody, Rabbit PAb
Human REG4	WB, ELISA	REG4 Antibody, Rabbit PAb (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description
REG1B	Human	Homo sapiens REG1B cDNA Clone
REG3A	Human	Homo sapiens REG3A cDNA Clone(NM_002580.1)
REG3A	Mouse	Mus musculus REG3A cDNA Clone
REG3D	Mouse	Mus musculus REG3D cDNA Clone
REG3G	Human	Homo sapiens REG3G cDNA Clone
REG4	Human	Homo sapiens REG4 cDNA Clone(NM_032044.2)
REG4	Mouse	Mus musculus REG4 cDNA Clone

REG1A Background

Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopathy. REG I has been shown to be crucial for induction of ductal epithelial cells to differentiate into insulin producing cells. Lithostathine-1-alpha, also known as Pancreatic stone protein, Pancreatic thread protein, Regenerating islet-derived protein 1-alpha, REG1A, REG-1-alpha, and PSPS, is highly expressed in fetal and infant brains. REG1A contains one C-type lectin domain and is a known growth factor affecting pancreatic islet beta cells. REG1A may act as an inhibitor of spontaneous calcium carbonate precipitation. It may also be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. REG1A has been reported to be expressed in human cancers, and it may be positively correlated with patient's prognosis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. High levels of REG1A expression by tumor cells are an independent predictor of a poor prognosis in patients with non-small cell lung cancer (NSCLC).

REG1A Related Studies

1. Boonyasrisawat W, et al. (2002) Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy. Southeast Asian J Trop Med Public Health. 33(2): 365-72.
2. Tezel E, et al. (2004) REG I as a marker for human pancreatic acinoductular cells. Hepatogastroenterology. 51(55): 91-6.
3. Geng J, et al. (2009) REG1A predicts recurrence in stage Ta/T1 bladder cancer. Eur J Surg Oncol. 35(8): 852-7.