Anti-REG1A Antibody

Cat: 11234-RP02
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Anti-REG1A Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-REG1A Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human REG1A
Immunogen
Recombinant Human REG1A protein (Catalog#11234-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human REG1A (rh REG1A; Catalog#11234-H08H; NP_002900.2; Met 1-Asn 166). REG1A specific IgG was purified by human REG1A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-REG1A Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-REG1A Antibody Alternative Names
Anti-ICRF Antibody;Anti-MGC12447 Antibody;Anti-P19 Antibody;Anti-PSP Antibody;Anti-PSPS Antibody;Anti-PSPS1 Antibody;Anti-PTP Antibody;Anti-R EG Antibody;Anti-REG Antibody;Anti-REG1A Antibody
REG1A Background Information

Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopathy. REG I has been shown to be crucial for induction of ductal epithelial cells to differentiate into some cells. Lithostathine-1-alpha, also known as Pancreatic stone protein, Pancreatic thread protein, Regenerating islet-derived protein 1-alpha, REG1A, REG-1-alpha, and PSPS, is highly expressed in fetal and infant brains. REG1A contains one C-type lectin domain and is a known growth factor affecting pancreatic islet beta cells. REG1A may act as an inhibitor of spontaneous calcium carbonate precipitation. It may also be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. REG1A has been reported to be expressed in human cancers, and it may be positively correlated with patient's prognosis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. High levels of REG1A expression by tumor cells are an independent predictor of a poor prognosis in patients with non-small cell lung cancer (NSCLC).

Full Name
regenerating family member 1 alpha
References
  • Boonyasrisawat W, et al. (2002) Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy. Southeast Asian J Trop Med Public Health. 33(2): 365-72.
  • Tezel E, et al. (2004) REG I as a marker for human pancreatic acinoductular cells. Hepatogastroenterology. 51(55): 91-6.
  • Geng J, et al. (2009) REG1A predicts recurrence in stage Ta/T1 bladder cancer. Eur J Surg Oncol. 35(8): 852-7.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-REG1A Antibody Rabbit Polyclonal ELISA,IHC-P 90162-T24
    Anti-REG1A Antibody Rabbit Polyclonal ELISA 11234-RP01
    Anti-REG1A Antibody Rabbit Polyclonal ELISA 11234-T16
    Anti-REG1A Antibody Mouse Monoclonal ELISA,ICC/IF,IF 11234-MM03
    Anti-REG1A Antibody Mouse Monoclonal IHC-P 11234-MM07
    Anti-REG1A Antibody Mouse Monoclonal ELISA 11234-MM09
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