Anti-MMP19 Antibody

Cat: 13912-RP01
Contact us:
All MMP19 Reagents
CRO Services
Product recommended

All MMP19 Reagents
Anti-MMP19 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-MMP19 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human MMP19
Recombinant Human RASI-1 / MMP19 protein (Catalog#13912-HNAE)
Produced in rabbits immunized with purified, recombinant Human RASI-1 / MMP19 (rh RASI-1 / MMP19; Catalog#13912-HNAE; Q99542-1; Leu101-Gly256). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-MMP19 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-MMP19 Antibody Alternative Names
Anti-MMP18 Antibody;Anti-RASI-1 Antibody
MMP19 Background Information

MMP19, also known as RASI-1, is a member of the peptidase M10A family. It contains 4 hemopexin-like domains and is expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. It is a matrix metalloproteinase (MMP). Proteins of the MMP family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP19 may play a role in pathological processes participating in rheumatoid arthritis (RA)-associated joint tissue destruction. Autoantigen anti-MMP19 are frequent in RA patients.

Full Name
matrix metallopeptidase 19
  • Cossins J., et al.,(1996), Identification of MMP-18, a putative novel human matrix metalloproteinase. Biochem. Biophys. Res. Commun. 228:494-498.
  • Pendas A.M., et al., (1997), Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location and tissue distribution.J. Biol. Chem. 272:4281-4286.
  • Kolb C., et al.,(1997), The matrix metalloproteinase RASI-1 is expressed in synovial blood vessels of a rheumatoid arthritis patient.Immunol. Lett. 57:83-88.
  • Product Description Host Clonality Application Catalog# (PDF)
    info info
    添加购物车成功! 添加购物车失败!