All RAB5 reagents are produced in house and quality controlled, including 1 RAB5 Antibody, 30 RAB5 Gene, 2 RAB5 qPCR. All RAB5 reagents are ready to use.
RAB5 antibodies are validated with different applications, which are IHC-P.
RAB5 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each RAB5 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Over-expression of RAB5A gene has been proved to be associated with neoplasia metastasis.Over-expression of RAB5A genes plays an important role in tumor invasion and metastatic phenotype formation of human lung adenocarcinoma cells; and antisense RNA can interrupt the translation of RAB5A gene.RAB5A was a directly target of miR-13a, and its mRNA and protein level was negatively regulated by miR-13a. Immunohistochemistry verified RAB5A was upregulated in breast cancer tissues. RAB5A gene was abnormally expressed in luteinized granulosa cells of obese patients with polycystic ovary syndrome, which may help explain high FSHR levels found in this syndrome.