|Catalog||Size (Price)||Quantity||In Stock||Operation||Other Information|
Prostatic acid Phosphatase / ACPP Antibody Datasheet
|Order or Inquire for Prostatic acid Phosphatase / ACPP Antibody product||Quality antibodies||Antibody production services|
Prostatic acid Phosphatase / ACPP Antibody Product Information
Recombinant Human Prostatic acid Phosphatase / ACPP protein (Catalog#10959-H08H)
|Antibody Type :||Mouse Monoclonal Antibody ( Mouse mAb Service Platform )|
Clone ID :
|Ig Type :||
|Formulation :||0.2 μm filtered solution in PBS with 5% trehalose|
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Prostatic acid Phosphatase / ACPP (rh Prostatic acid Phosphatase / ACPP; Catalog#10959-H08H; NP_001127666.1; Met 1-Lys 382). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Prostatic acid Phosphatase / ACPP Antibody Usage Guide
Human Prostatic acid Phosphatase / ACPP
No cross-reactivity in ELISA with
Human cell lysate (293 cell line)
|Direct ELISA :||This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human ACPP.|
|Storage :||This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Prostatic acid Phosphatase / ACPP Antibody Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|Prostatic acid Phosphatase/ACPP||Human||Prostatic acid Phosphatase/ACPP Protein, Recombinant||10959-H08H|
|Prostatic acid Phosphatase/ACPP||Mouse||ACPP / PSAP Protein, Recombinant||51018-M08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|Human Prostatic acid Phosphatase/ACPP||WB, ELISA||Prostatic acid Phosphatase / ACPP Antibody||10959-MM03|
|Human Prostatic acid Phosphatase/ACPP||ELISA||Prostatic acid Phosphatase / ACPP Antibody||10959-MM06|
|Human Prostatic acid Phosphatase/ACPP||WB, ELISA||Prostatic acid Phosphatase/ACPP Antibody (Antigen Affinity Purified)||10959-RP02|
Prostatic acid Phosphatase / ACPP Antibody Background
Prostatic acid phosphatase, also known as ACPP, is a secreted and a single-pass type I membrane protein which belongs to thehistidine acid phosphatase family. ACPP / PSAP is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of ACPP / PSAP are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells, such as sickle-cell disease or multiple myeloma or lysosomal storage diseases, such as Gaucher's disease, will show moderately increased levels. ACPP / PSAP was used to monitor and assess progression of prostate cancer until the introduction of prostate specific antigen (PSA), which has now largely displaced it. ACPP / PSAP has a role in prognosticating intermediate and high-risk prostate cancer, it has led to renewed interest in this marker. Its physiological function may be associated with the liquefaction process of semen. ACPP / PSAP may play an important role in the transmission of HIV. ACPP / PSAP forms fibers made of amyloid. There fibers capture HIV virions promoting their attachment to target cells. The association of ACPP / PSAP with HIV may increase the ability of the virus to infect human cells "by several orders of magnitude."ACPP / PSAP may be a future target of efforts to combat the spread of HIV infection.
- Genega EM, et al., 2000, Mod. Pathol.13 (11): 1186-91.
- Taira A, et al.,2007, Oncology. 21 (8): 1003-10.
- Munch J, et al., 2007, Cell131 (6): 1059-71.
- Zylka MJ, et al.,2008, Neuron. 60 (1): 111-22.