Prolactin Protein

Prolactin Products

Prolactin Protein, Recombinant

Molecule	Species	Description	Cat. No
Prolactin	Mouse	PRL/Prolactin Protein, Recombinant	50367-M08B

Prolactin cDNA Clone

Molecule	Species	Description	Cat. No
Prolactin	Human	Human PRL/Prolactin cDNA Clone / ORF Clone	HG10275-M
Prolactin	Mouse	Mouse PRL/Prolactin cDNA Clone / ORF Clone	MG50367-M

Prolactin Alternative Names

Prolactin, PRL, RP3-404K8.1 [Homo sapiens]

Prolactin, Prl, RP23-351I6.2, AV290867, Prl1a1 [Mus musculus]

Prolactin Background

Prolactin has an important role in the innate and adaptive immune response. Increased prolactin levels have been described in autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome, and systemic sclerosis among others. PRL affects metabolic homeostasis by regulating key enzymes and transporters that are associated with glucose and lipid metabolism in several target organs. In adipose tissue, PRL generally suppresses lipid storage and adipokine release. Prolactin has recently been recognized as potent platelet aggregation co-activator, and have therefore been postulated as an additional risk factor for both arterial and venous thrombosis. Prolactin has been shown to stimulate intestinal calcium absorption, increase bone turnover, and reduce renal calcium excretion. In addition, Prolactin is involved in normal breast development and lactation, has been hypothesized to be important in the etiology of breast cancer.

Prolactin Related Studies

1. Jara LJ, et al. (2011) Prolactin and autoimmunity. Clin Rev Allergy Immunol. 40(1): 50-9.
2. Urban A, et al. (2007) Prolactin as a factor for increased platelet aggregation. Neuro Endocrinol Lett. 28(4): 518-23.
3. Charoenphandhu N, et al. (2007) Prolactin is an important regulator of intestinal calcium transport. Can J Physiol Pharmacol. 85(6): 569-81.
4. Tworoger SS, et al. (2006) Prolactin and breast cancer risk. Cancer Lett. 243(2): 160-9.
5. Ben-Jonathan N, et al. (2006) Focus on prolactin as a metabolic hormone. Trends Endocrinol Metab. 17(3): 110-6.