Profilin-2 (Protein | Antibody | cDNA Clone | ELISA Kit)

All Profilin-2 reagents are produced in house and quality controlled, including 2 Profilin-2 Antibody, 47 Profilin-2 Gene, 1 Profilin-2 Protein, 2 Profilin-2 qPCR. All Profilin-2 reagents are ready to use.

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Profilin-2 Background

Profilin 2, also known as PFN2,is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. Profilin 2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. Profilin 2 is thought to regulate actin polymerization in response to extracellular signals. It inhibits the formation of IP3 and DG by binding to PIP2.

Profilin-2 References

  • Da Silva. et al., 2003, J Cell Biol. 162 (7): 1267-79.
  • Honore B. et al., 1993, FEBS Lett. 330 (2): 151-5.
  • Joensuu T. et al., 1997, Genomics. 38 (3): 255-63.