All Profilin-2 reagents are produced in house and quality controlled, including 2 Profilin-2 Antibody, 47 Profilin-2 Gene, 1 Profilin-2 Protein, 2 Profilin-2 qPCR. All Profilin-2 reagents are ready to use.
Recombinant Profilin-2 proteins are expressed by E. coli with fusion tags as N-His.
Profilin-2antibodies are validated with different applications, which are WB, ELISA, IHC-P.
Profilin-2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Profilin-2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Profilin 2, also known as PFN2, is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. Profilin 2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. Profilin 2 is thought to regulate actin polymerization in response to extracellular signals. It inhibits the formation of IP3 and DG by binding to PIP2.