0 products, total $0.+86-400-890-9989      Login |  Register 中文한국어

Browse By Molecule:

Your Position: Home > Phosphatase & Phosphatase Regulator

Phosphatase & Phosphatase Regulator

A phosphatase is an enzyme that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group.

Sino Biological provides a comprehensive set of tools for study of phosphatases and their regulators, including recombinant proteins, antibodies (rabbit MAbs, mouse MAbs, rabbit PAbs), ELIASA kits, and gene cDNA clones.

Phosphatase & Regulator Products

  Please click the molecular formulas to find products that you are interested.

   *   Being developed. Tell us your requirement so that the products of interest be placed on the priority list.

Acid Phosphatase

Alkaline Phosphatase

Dual Specificity Phosphatase

  • CDC25A*
  • CDC25C*

Lipid Phosphatase

  • PTEN*

Protein Histidine Phosphatase

Protein Serine/Threonine Phosphatase

  • PPP1A*
  • PPP1CA*
  • PPM1B*
  • PPP1R14D*
  • PPP5C*
  • PPP2CA*
  • PPTC7*

Protein Tyrosine Phosphatase

  • PTP4A3*
  • PTPN6*
  • PTPN12 / PTP-PEST*
  • MEG2 / PTPN9*

Other Phosphatases

Phosphatase Regulator

Phosphatase & Regulator Background

A phosphatase is an enzyme that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters into a phosphate ion and a molecule with a free hydroxyl group. This action is directly opposite to that of phosphorylases and kinases. Phosphorylation and dephosphorylation usually results in a functional change of the substrate by changing enzyme activity, intracellular location, or association with other proteins. Protein phosphatases and protein kinases are particularly prominent in signal transduction and are known to regulate the majority of cell processes, such as cell growth, differentiation, metabolism, gene transcription, and so on. Phosphatases can be subdivided based upon their substrate specificity. There are tyrosine-specific phosphatases, serine/threonine specific phosphatases, dual specificity phosphatases, histidine phosphatase and lipid phosphatase.

Phosphatase & Regulator Related Studies

    1. Vintonyak VV, et al. (2009) The therapeutic potential of phosphatase inhibitors. Curr Opin Chem Biol. 13(3):272-83.
    2. Nicolaou P, et al. Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol. 47(3):365-71.
    3. Roy J, et al. (2009) Cracking the phosphatase code: docking interactions determine substrate specificity. Sci Signal. 2(100):re9.
    4. Whyte MP. (2010) Physiological role of alkaline phosphatase explored in hypophosphatasia. Ann N Y Acad Sci. 1192(1):190-200.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
_×