Text Size:AAA

Peroxiredoxin 6/PRDX6 Protein, Antibody, ELISA Kit, cDNA Clone

Peroxiredoxin 6/PRDX6 Related Areas

Peroxiredoxin 6/PRDX6 Related Pathways

Peroxiredoxin 6/PRDX6 Related Product

    Peroxiredoxin 6/PRDX6 Summary & Protein Information

    Peroxiredoxin 6/PRDX6 Background

    Gene Summary: The protein encoded by PRDX6 gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
    General information above from NCBI
    Catalytic activity: 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
    2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
    Subunit structure: Homotetramer. Interacts with GSTP1; mediates PRDX6 glutathionylation and regeneration. May interact with HTR2A (By similarity). Interacts with APEX1 and STH. May interact with FAM168B.
    Subcellular location: Cytoplasm. Lysosome (By similarity). Cytoplasmic vesicle (By similarity). Note=Also found in lung secretory organelles (By similarity).
    Sequence similarity: Belongs to the AhpC/TSA family. Rehydrin subfamily.
    Contains 1 thioredoxin domain.
    General information above from UniProt

    Peroxiredoxin 6/PRDX6 Alternative Name

    PRDX6,1-Cys,aiPLA2,AOP2,KIAA0106,MGC46173,NSGPx,p29,Peroxiredoxin 6,PRX, [human]
    Prdx6,1-cysPrx,9430088D19Rik,AA690119,Aop2,Aop2-rs3,Brp-12,CP-3,GPx,KIAA0106,Ltw4,Ltw-4,Lvtw-4,Peroxiredoxin 6, [mouse]

    Peroxiredoxin 6/PRDX6 Related Studies

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"