Anti-Peroxiredoxin 1 Antibody

Cat: 11194-RP02
Contact us:
All Peroxiredoxin 1 Reagents
CRO Services
Product recommended

All Peroxiredoxin 1 Reagents
Anti-Peroxiredoxin 1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Peroxiredoxin 1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human Peroxiredoxin 1
Recombinant Human Peroxiredoxin 1 / PRDX1 protein (Catalog#11194-H08E)
Produced in rabbits immunized with purified, recombinant Human Peroxiredoxin 1 / PRDX1 (rh Peroxiredoxin 1 / PRDX1; Catalog#11194-H08E; NP_002565.1; Met 1-Lys 199). Peroxiredoxin 1 / PRDX1 specific IgG was purified by Human Peroxiredoxin 1 / PRDX1 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Peroxiredoxin 1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:2000  
ELISA 1:5000-1:10000  
IP 4-6 μL/mg of lysate  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Peroxiredoxin 1 Antibody (Rabbit Polyclonal antibody) Images
Human Peroxiredoxin 1/PRDX1 Immunoprecipitation(IP) 8064

PRDX1 was immunoprecipitated using:

Lane A:0.5 mg A431 Whole Cell Lysate

2 µL anti-PRDX1 rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose.

Primary antibody:

Anti-PRDX1 rabbit polyclonal antibody,at 1:200 dilution

Secondary antibody:

Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution

Developed using the odssey technique.

Performed under reducing conditions.

Predicted band size: 22 kDa

Observed band size: 22 kDa

Human Peroxiredoxin 1/PRDX1 Western blot (WB) 13359

Anti-PRDX1 rabbit polyclonal antibody at 1:500 dilution

Lane A: A431 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.


Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:22 kDa

Observed band size:22 kDa

Anti-Peroxiredoxin 1 Antibody Alternative Names
Anti-MSP23 Antibody;Anti-NKEF-A Antibody;Anti-NKEFA Antibody;Anti-PAG Antibody;Anti-PAGA Antibody;Anti-PAGB Antibody;Anti-PRX1 Antibody;Anti-PRXI Antibody;Anti-TDPX2 Antibody
Peroxiredoxin 1 Background Information

Peroxiredoxin-1, also known as Thioredoxin peroxidase 2, Natural killer cell-enhancing factor A, PRDX1, and PAGA, is a member of the ahpC/TSA family. Peroxiredoxin-1 is constitutively expressed in most human cells. It is induced to higher levels upon serum stimulation in untransformed and transformed cells. Peroxiredoxins (PRDXs) are a family of antioxidant enzymes that are also known as scavengers of peroxide in mammalian cells. The overexpression of Peroxiredoxin-1, which is one of the peroxiredoxins that is a ubiquitously expressed protein, was related to a poor prognosis in several types of human cancers. Peroxiredoxin-1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-1 Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The reduced Peroxiredoxin-1 expression is an important factor in esophageal squamous cancer progression and could serve as a useful prognostic marker.

Full Name
peroxiredoxin 1
  • Neumann, CA. et al., 2003, Nature 424 (6948): 561-5
  • Gisin, J. et al., 2005, J Clin Pathol. 58 (11): 1229-31.
  • Hoshino, I. et al., 2007, Oncol Rep. 18 (4): 867-71.
  • Cao, J. et al., 2009, EMBO J. 28 (10): 1505-17.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Peroxiredoxin 1 Antibody Rabbit Polyclonal ELISA 11194-RP01
    info info
    添加购物车成功! 添加购物车失败!