Anti-Peroxiredoxin 1 Antibody

Cat: 11194-RP01
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All Peroxiredoxin 1 Reagents
CRO Services
Product recommended

All Peroxiredoxin 1 Reagents
Anti-Peroxiredoxin 1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Peroxiredoxin 1 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human Peroxiredoxin 1
Immunogen
Recombinant Human Peroxiredoxin 1 / PRDX1 protein (Catalog#11194-H08E)
Preparation
Produced in rabbits immunized with purified, recombinant Human Peroxiredoxin 1 / PRDX1 (rh Peroxiredoxin 1 / PRDX1; Catalog#11194-H08E; NP_002565.1; Met 1-Lys 199). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Peroxiredoxin 1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Peroxiredoxin 1 Antibody Alternative Names
Anti-MSP23 Antibody;Anti-NKEF-A Antibody;Anti-NKEFA Antibody;Anti-PAG Antibody;Anti-PAGA Antibody;Anti-PAGB Antibody;Anti-PRX1 Antibody;Anti-PRXI Antibody;Anti-TDPX2 Antibody
Peroxiredoxin 1 Background Information

Peroxiredoxin-1, also known as Thioredoxin peroxidase 2, Natural killer cell-enhancing factor A, PRDX1, and PAGA, is a member of the ahpC/TSA family. Peroxiredoxin-1 is constitutively expressed in most human cells. It is induced to higher levels upon serum stimulation in untransformed and transformed cells. Peroxiredoxins (PRDXs) are a family of antioxidant enzymes that are also known as scavengers of peroxide in mammalian cells. The overexpression of Peroxiredoxin-1, which is one of the peroxiredoxins that is a ubiquitously expressed protein, was related to a poor prognosis in several types of human cancers. Peroxiredoxin-1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-1 Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The reduced Peroxiredoxin-1 expression is an important factor in esophageal squamous cancer progression and could serve as a useful prognostic marker.

Full Name
peroxiredoxin 1
References
  • Neumann, CA. et al., 2003, Nature 424 (6948): 561-5
  • Gisin, J. et al., 2005, J Clin Pathol. 58 (11): 1229-31.
  • Hoshino, I. et al., 2007, Oncol Rep. 18 (4): 867-71.
  • Cao, J. et al., 2009, EMBO J. 28 (10): 1505-17.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Peroxiredoxin 1 Antibody Rabbit Polyclonal WB,ELISA,IP 11194-RP02
    info info
    添加购物车成功! 添加购物车失败!