Anti-Periostin Antibody

Cat: 10299-RP02

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Anti-Periostin Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Periostin Antibody
Validated applications
ELISA,IHC-P
Species reactivity
Reacts with: Human
Specificity
Human Periostin
Immunogen
Recombinant Human Periostin / POSTN / OSF-2 protein (Catalog#10299-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human Periostin / POSTN / OSF-2 (rh Periostin / POSTN / OSF-2; Catalog#10299-H08H; NP_001129407.1; Met 1-Gln 781). Periostin / POSTN / OSF-2 specific IgG was purified by Human Periostin / POSTN / OSF-2 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Periostin Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
IHC-P 1:500-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Periostin Antibody (Rabbit Polyclonal antibody) Images
Human Periostin/POSTN/OSF-2 Immunohistochemistry(IHC) 3754
Immunochemical staining of human POSTN in human stomach with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Human Periostin/POSTN/OSF-2 Immunohistochemistry(IHC) 3755
Immunochemical staining of human POSTN in human colon with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Human Periostin/POSTN/OSF-2 Immunohistochemistry(IHC) 3756
Immunochemical staining of human POSTN in human colon carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Human Periostin/POSTN/OSF-2 Immunohistochemistry(IHC) 3757
Immunochemical staining of human POSTN in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Anti-Periostin Antibody Alternative Names
Anti-OSF-2 Antibody;Anti-OSF2 Antibody;Anti-PDLPOSTN Antibody;Anti-periostin Antibody;Anti-PN Antibody
Periostin Background Information

Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced in areas of tissue injury or areas with ongoing cellular re-organization. In the adult heart Postn is induced in the ventricles following myocardial infarction, pressure overload stimulation, or generalized cardiomyopathy. Although the detailed function of Postn is still unclear, Postn-integrin interaction is thought to be involved in tumor development. Postn is frequently overexpressed in various types of human cancers, stimulating metastatic growth by promoting cancer cell survival, invasion and angiogenesis, and can be a useful marker to predict the behavior of cancer.

Full Name
periostin, osteoblast specific factor
References
  • Kudo,Y. et al., 2007, Histol Histopathol. 22 (10):1167-1174.
  • Li, J.S. et al., 2007, World J Gastroenterol. 13 (39): 5261-5266.
  • Oku, E. et al., 2008, Int J Hematol. 88 (1): 57-63.
  • Hamilton, D.W. et al., 2008, J Cell Commun Signal. 2(1-2):9-17.
  • Puglisi, F.J et al., 2008, Clin Pathol. 61 (4): 494-498.
  • Conway, S. J. et al., 2008, Curr Genomics. 9 (8): 548-555.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Periostin Antibody Rabbit Monoclonal ELISA 50450-R031
    Anti-Periostin Antibody Rabbit Polyclonal ELISA,IHC-P 50450-RP02
    Anti-Periostin Antibody Rabbit Polyclonal ELISA 50450-RP01
    Anti-Periostin Antibody Rabbit Polyclonal ELISA,IHC-P 10299-T24
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