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Periostin / POSTN Antibody, Rabbit PAb
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Periostin / POSTN Antibody, Rabbit PAb PDF Download

Catalog   Size (Price) Quantity In Stock Operation
50450-RP01  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

Periostin / POSTN Antibody Datasheet

  Order or Inquire for Periostin / POSTN Antibody product Quality antibodies Antibody production services
  Detection limit is 0.039 ng/well in ELISA
 

Periostin / POSTN Antibody Product Information

Immunogen :

Recombinant Mouse Periostin / POSTN protein (Catalog#50450-M08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type :

Rabbit IgG

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

Produced in rabbits immunized with purified, recombinant Mouse Periostin / POSTN (rM Periostin / POSTN; Catalog#50450-M08H; NP_056599.1; Met 1-Gln 811). Total IgG was purified by Protein A affinity chromatography.

Periostin / POSTN Antibody Usage Guide

Specificity :

Mouse Periostin / POSTN

Direct ELISA : This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Mouse POSTN. The detection limit for Mouse POSTN is less than 0.039 ng/well.
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Periostin / POSTN Antibody Related Products & Topics

Related Areas:

Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>Periostin/POSTN/OSF-2

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
POSTN/OSF-2 Human Periostin/POSTN/OSF-2 Protein, Recombinant 10299-H08H
POSTN/OSF-2 Mouse Periostin/POSTN/OSF-2 Protein, Recombinant 50450-M08H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human POSTN/OSF-2 WB, ELISA, IHC-P Periostin / POSTN / OSF-2 Antibody (Antigen Affinity Purified) 10299-RP02
Mouse POSTN/OSF-2 ELISA Periostin / POSTN Antibody 50450-RP01
Mouse POSTN/OSF-2 ELISA Periostin / POSTN Antibody (Antigen Affinity Purified) 50450-RP02
Mouse POSTN/OSF-2 WB, ELISA Periostin / POSTN Antibody 50450-R031

Periostin / POSTN Antibody Background

Periostin (POSTN), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced in areas of tissue injury or areas with ongoing cellular re-organization. In the adult heart Postn is induced in the ventricles following myocardial infarction, pressure overload stimulation, or generalized cardiomyopathy. Although the detailed function of Postn is still unclear, Postn-integrin interaction is thought to be involved in tumor development. Postn is frequently overexpressed in various types of human cancers, stimulating metastatic growth by promoting cancer cell survival, invasion and angiogenesis, and can be a useful marker to predict the behavior of cancer.

References

  1. Kudo,Y. et al., 2007, Histol Histopathol. 22 (10):1167-1174.
  2. Li, J.S. et al., 2007, World J Gastroenterol. 13 (39): 5261-5266.
  3. Oku, E. et al., 2008, Int J Hematol. 88 (1): 57-63.
  4. Hamilton, D.W. et al., 2008, J Cell Commun Signal. 2 (1-2):9-17.
  5. Puglisi, F.J et al., 2008, Clin Pathol. 61 (4): 494-498.
  6. Conway, S. J. et al., 2008, Curr Genomics. 9 (8): 548-555.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"