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PTGDS / L-PGDS

PTGDS / L-PGDS Protein & Antibody

Entrez Gene Summary for PTGDS / L-PGDS


The protein encoded by this PTGDS gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PTGDS functions as a neuromodulator as well as a trophic factor in the central nervous system. PTGDS is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This PTGDS gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]

OMIM-Description for PTGDS / L-PGDS


Prostaglandin D2 (PGD2) functions as a neuromodulator and/or trophic factor in the central nervous system. Glutathione (GSH)-independent PGD synthase catalyzes the conversion of prostaglandin H2 (PGH2) to PGD2 in the presence of various sulfhydryl compounds. The enzyme is responsible for biosynthesis of PTGDS in the brain (Nagata et al., 1991).

.zh=PTGDS / L-PGDS


Prostaglandin-H2 D-isomerase (PTGDS) is an enzyme that in humans is encoded by the PTGDS gene.
The protein encoded by this PTGDS gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This PTGDS gene is preferentially expressed in brain. Studies with transgenic mice over-expressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Furthermore, PTGDS and its product PGD2 are elevated in the bald-scalp areas of men with male pattern baldness (androgenetic alopecia).

PTGDS / L-PGDS Alternative Names

PGD2,PGDS,prostaglandin-H2 D-isomerase,beta-trace protein,cerebrin-28,glutathione-independent PGD synthase,glutathione-independent PGD synthetase,lipocalin-type prostaglandin D synthase,LPGDS,L-PGDS,PDS,PGD2 synthase,PGDS2,prostaglandin D synthase,prostaglandin-D2 synthase,RP11-229P13.6, [human]
prostaglandin-H2 D-isomerase,21kDa,brain),glutathione-independent PGD synthase,glutathione-independent PGD synthetase,lipocalin-type prostaglandin-D synthase,L-PGDS,PGD2,PGD2 synthase,PGDS,PGDS2,prostaglandin D2 synthase (21 kDa,prostaglandin-D2 synthase,Ptgs3,RP23-47P18.11-006, [mouse]

PTGDS / L-PGDS Related Products

PTGDS / L-PGDS Proteins

Product nameProduct name
Human PTGDS / L-PGDS Protein (His Tag)

PTGDS / L-PGDS Antibodies

Product nameProduct name
PTGDS / L-PGDS Antibody, Rabbit PAb, Antigen Affinity Purified

PTGDS / L-PGDS cDNA Clones

Product nameProduct name
Human PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tagHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone)Mouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tagRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone)Human PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tagCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tagMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone)Mouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedHuman PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedMouse PTGDS Gene cDNA Clone (full-length ORF Clone)Rat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedRat PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedCynomolgus monkey PTGDS Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged

PTGDS / L-PGDS ELISA

Product nameProduct name
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"