DNA-PKcs (Protein|Antibody|cDNA Clone|ELISA Kit)

All DNA-PKcs reagents are produced in house and quality controlled, including 2 DNA-PKcs Antibody. All DNA-PKcs reagents are ready to use.

DNA-PKcs antibodies are validated with different applications, which are IHC-P, ICC/IF, IF.

DNA-PKcs Antibody (2)

Application Clonality
Host

Anti-DNA-PKcs Antibody

101038-T08

Specificity: Human

Application: IHC-P

Clonality: PAb

Human PRKDC Immunohistochemistry(IHC) 3735

Anti-DNA-PKcs Antibody

101038-T10

Specificity: Human

Application: IHC-P,ICC/IF,IF

Clonality: PAb

Human PRKDC Immunohistochemistry(IHC) 15709
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PRKDC encodes for DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a kinase that forms part of a complex (DNA-dependent protein kinase [DNA-PK]) crucial for DNA double-strand break repair and V(D)J recombination. PRKDC expression was significantly increased in breast cancer tissue samples compared with NATs. High PRKDC expression was associated with higher tumor grade (P=.1), positive lymph node metastasis (P=.357) and chemoresistance (P=.6). Furthermore, PRKDC expression was significantly correlated with OS in breast cancer patients with (.11) or without (P=.216) receiving chemotherapy.Collectively,PRKDC is a prognostic biomarker for chemoresistance in breast cancer patients.
Antibody
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