Anti-PMP2 Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human PMP2 protein (Catalog#11426-H07E)
Produced in rabbits immunized with purified, recombinant Human PMP2 (rh PMP2; Catalog#11426-H07E; NP_002668.1; Ser 2-Val 132). Total IgG was purified by Protein A affinity chromatography
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-PMP2 Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-PMP2 Antibody Alternative Names
Anti-FABP8 Antibody;Anti-M-FABP Antibody;Anti-MP2 Antibody;Anti-P2 Antibody
PMP2 Background Information
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells of the central and peripheral nervous systems, the oligodendrocytes and Schwann cells, respectively. PMP2 may play a role in lipid transport protein in Schwann cells. It forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
peripheral myelin protein 2
Hayasaka, K. et al., 1993, Genomics. 18 (2): 244-8. Polverini, E. et al., 2006, J Struct Biol. 153 (3): 253-63. Gould,R.M. et al., 2008, Neuron Glia Biol. 4 (2):137-52.