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> PLA2G2E PLA2G2E
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. PLA2G2E has a preference for arachidonic-containing phospholipids.
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PLA2G2E Related Products
PLA2G2E Proteins
PLA2G2E Antibodies
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PLA2G2E cDNA Clones
PLA2G2E Related Areas
Enzyme>>Lipid Metabolism Enzymes>>PLA2G2E
Cardiovascular>>Lipid Metabolism>>Lipid Metabolism Enzymes>>PLA2G2E
PLA2G2E Related Pathways
PLA2G2E Alternative Names
PLA2G2E, GIIE sPLA2, OTTHUMP00000002789 [Homo sapiens]
PLA2G2E, RP23-352K10.7 [Mus musculus]
Summaries for PLA2G2E
Human PLA2G2E Protein General Information
| Protein names |
Group IIE secretory phospholipase A2 |
| Sequence length |
142 AA. |
| Domain |
Signal |
| Sequence similarities: |
Belongs to the phospholipase A2 family. |
| Cofactor: |
Binds 1 calcium ion per subunit. |
| Catalytic activity |
Phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. |
| Subcellular location: | Secreted. |
| Tissue specificity |
Restricted to the brain, heart, lung, and placenta. |
General information above from UniProt
Function for PLA2G2E Protein
UniProtKB:
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. PLA2G2E has a preference for arachidonic-containing phospholipids.
Genatlas:
- PLA2G2E is involved in the antipathogen response and in inflammatory process
