Anti-PIGR Antibody

Cat: 10131-MM05
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Anti-PIGR Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-PIGR Antibody
Validated applications
ELISA,ELISA(Det)
Species reactivity
Reacts with: Human
Specificity
Human PIGR
Immunogen
Recombinant Human PIGR protein (Catalog#10131-H08H)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PIGR extracellular domain (rh PIGR; Catalog#10131-H08H; NP_002635.2; Met 1-Arg 638). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Source
Monoclonal Mouse IgG Clone #4G1B11A5
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-PIGR Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  
ELISA(Det) 1:1000-1:10000 This antibody will detect Human PIGR in ELISA pair set (Catalog: # SEK10131). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10131-MM06).

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-PIGR Antibody Alternative Names
Anti-FLJ22667 Antibody;Anti-MGC125361 Antibody;Anti-MGC125362 Antibody;Anti-PIGR Antibody
PIGR Background Information

Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.

Full Name
polymeric immunoglobulin receptor
References
  • Coyne, R. S. et al., 1995, J. Biol. Chem. 269 (50) :31620-31625. 
  • Kaetzel,C.S., 2001,  Curr Biol. 11(1): R35-38.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-PIGR Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 50119-R040
    Anti-PIGR Antibody Rabbit Polyclonal ELISA 50119-RP01
    Anti-PIGR Antibody Rabbit Polyclonal ELISA 50119-RP02
    Anti-PIGR Antibody Mouse Monoclonal ELISA(Cap) 10131-MM06
    Anti-PIGR Antibody Rabbit Polyclonal ELISA 10131-RP02
    Anti-PIGR Antibody Rabbit Monoclonal IHC-P 10131-R007
    Anti-PIGR Antibody Rabbit Polyclonal ELISA 10131-RP01
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