Anti-PHYH Antibody

Cat: 13368-RP02

Contact us:


All PHYH Reagents

CRO Services

Product recommended

All PHYH Reagents

Anti-PHYH Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-PHYH Antibody
Validated applications
Species reactivity
Reacts with: Human
Human PHYH
Recombinant Human PHYH protein (Catalog#13368-HNAE)
Produced in rabbits immunized with purified, recombinant Human PHYH (rh PHYH; Catalog#13368-HNAE; O14832; Ser31-Leu338). PHYH specific IgG was purified by Human PHYH affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Anti-PHYH Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution Notes
ELISA 1:5000-1:10000  
IHC-P 1:500-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-PHYH Antibody (Rabbit Polyclonal antibody) Images

Human PHYH Immunohistochemistry(IHC) 3780
Immunochemical staining of human PHYH in human spleen with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Human PHYH Immunohistochemistry(IHC) 3781
Immunochemical staining of human PHYH in human liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Human PHYH Immunohistochemistry(IHC) 3782
Immunochemical staining of human PHYH in human kidney with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Anti-PHYH Antibody Alternative Names

Anti-LN1 Antibody;Anti-LNAP1 Antibody;Anti-PAHX Antibody;Anti-PHYH1 Antibody;Anti-RD Antibody

PHYH Background Information

PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentosa, peripheral neuropathy, cerebellar ataxia, and elevated protein levels in the cerebrospinal fluid (CSF). Patients exhibit accumulation of the branched-chain fatty acid, phytanic acid, in blood and tissues.

Full Name
phytanoyl-CoA 2-hydroxylase
  • Mihalik SJ, et al. (1997) Identification of PAHX, a Refsum disease gene. Nat Genet. 17(2): 185-9.
  • McDonough MA, et al. (2005) Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease. J Biol Chem. 280(49):41101-10.
  • Jansen GA, et al. (1998) Characterization of phytanoyl-Coenzyme A hydroxylase in human liver and activity measurements in patients with peroxisomal disorders. Clin Chim Acta. 271 (2):203-11.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-PHYH Antibody Rabbit Monoclonal ELISA 13368-R002
    Anti-PHYH Antibody Rabbit Polyclonal ELISA 13368-RP01
    Anti-PHYH Antibody Mouse Monoclonal ELISA 13368-MM01
    Anti-PHYH Antibody Mouse Monoclonal IHC-P 13368-MM03
    info info
    添加购物车成功! 添加购物车失败!