Anti-PEDF Antibody

Cat: 11104-RP01
Contact us:
All PEDF Reagents
CRO Services
Product recommended

All PEDF Reagents
Anti-PEDF Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-PEDF Antibody
Validated applications
Species reactivity
Reacts with: Human
Human PEDF
Recombinant Human SerpinF1 protein (Catalog#11104-H08H)
Produced in rabbits immunized with purified, recombinant Human SerpinF1 (rh SerpinF1; Catalog#11104-H08H; NP_002606.3; Met 1-Pro 418). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-PEDF Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-PEDF Antibody Alternative Names
Anti-EPC-1 Antibody;Anti-OI12 Antibody;Anti-OI6 Antibody;Anti-PEDF Antibody;Anti-PIG35 Antibody
PEDF Background Information

Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein which has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression.

Full Name
serpin peptidase inhibitor, clade F,member 1
  • Ren, JG. et al., 2005, Med Hypotheses. 64 (1): 74-8.
  • Filleur, S. et al., 2009. J Cell Biochem. 106 (5): 769-75.
  • Kawaguchi, T. et al., 2010, Curr Mol Med. 10 (3): 302-11.
  • Yamagishi, SI. et al., 2010, Curr Mol Med. 10 (3): 284-91.
  • Nakamura, T. et al., 2010, Curr Mol Med. 10 (3): 312-6.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-PEDF Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 80481-T60
    Anti-PEDF Antibody Rabbit Polyclonal ELISA 80481-T16
    Anti-PEDF Antibody Rabbit Polyclonal WB,ELISA,IHC-P 80481-T56
    Anti-PEDF Antibody Rabbit Monoclonal ELISA 80481-R061
    Anti-PEDF Antibody Rabbit Polyclonal WB,IHC-P,IP 80481-T44
    Anti-PEDF Antibody Rabbit Polyclonal ELISA 11104-T16
    Anti-PEDF Antibody Rabbit Polyclonal WB,ELISA,IP 11104-RP02
    Anti-PEDF Antibody Rabbit Monoclonal ELISA 11104-R013
    Anti-PEDF Antibody Rabbit Monoclonal WB 11104-R033
    info info
    添加购物车成功! 添加购物车失败!