|Recombinant Human PDZD11 / PDZK11 protein (Catalog#12188-H07E)|
|0.2 μm filtered solution in PBS with 5% trehalose|
|Produced in rabbits immunized with purified, recombinant Human PDZD11 / PDZK11 (rh PDZD11 / PDZK11; Catalog#12188-H07E; NP_057568.1; Asp 2-His 140). PDZD11 / PDZK11 specific IgG was purified by Human PDZD11 / PDZK11 affinity chromatography.|
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human PDZD11. The detection limit for Human PDZD11 is approximately 0.039 ng/well.
IHC-P: 0.1-1 μg/mL
PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein which contains one PDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Full-length human PDZD11 shares 97% amino acids (aa) identity with mouse PDZD11.