PDGFRB Protein & Antibody (CD140b)

Platelet-Derived Growth Factor Receptor Beta (Cluster of Differentiation 140b)

PDGFRB Products

PDGFRB Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
PDGFRB/CD140b	Human	PDGFRB/CD140b Protein, Recombinant	10514-H03H
PDGFRB/CD140b	Human	PDGFRB/CD140b Protein, Recombinant	10514-H08H
PDGFRB	Rat	PDGFRB / PDGFR-1 Protein, Recombinant	80347-R08H

PDGFRB Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human PDGFRB/CD140b	ELISA	PDGFRB / CD140b Antibody	10514-MM10
Human PDGFRB/CD140b	ELISA	Mouse Monoclonal Antibody	10514-MM11
Human PDGFRB/CD140b	ELISA	PDGFRB / CD140b Antibody	10514-MM12
Human PDGFRB/CD140b	WB, ELISA	Rabbit Polyclonal Antibody	10514-RP01
Human PDGFRB/CD140b	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10514-RP02

PDGFRB ELISA Kit

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human PDGFRB/CD140b	ELISA	PDGFRB/CD140b ELISA Kit	SEK10514

PDGFRB cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
PDGFRB/CD140b	Human	Homo sapiens PDGFRB/CD140b cDNA Clone(NM_002609.3)	HG10514-M
PDGFRB/CD140b	Rat	PDGFRB cDNA Clone / ORF Clone	RG80347-G
PDGFRB/CD140b	Cynomolgus	Cynomolgus monkey PDGFRB Gene cDNA Clone / ORF Clone	CG90215-G

PDGFRB Related Areas

Cardiovascular>>Platelet>>PDGFRB/CD140b

Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>PDGFRB/CD140b

Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>PDGFRB/CD140b

Cancer>>Cancer Stem Cell (CSC)>>PDGFRB/CD140b

Cancer>>Cancer Biomarkers>>PDGFRB/CD140b

Cancer>>Growth factor & Receptor>>PDGF & Receptor>>PDGFRB/CD140b

Cancer>>Growth factor & Receptor>>Receptor Tyrosine Kinase>>PDGFRB/CD140b

Immunology>>Cluster of Differentiation>>Other>>PDGFRB/CD140b

PDGFRB Alternative Names

PDGFRB, CD140B, PDGFR, PDGFR1, JTK12 [Homo sapiens]

Pdgfrb, CD140b, Pdgfr, AI528809 [Mus musculus]

PDGFRB Related Products

Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
PDGF-C	Human	PDGF-C/Fc Protein, Recombinant
PDGF-C	Mouse	PDGF-C Protein, Recombinant
PDGF-D	Human	PDGF-D/Fc Protein, Recombinant
PDGFRA/CD140a	Human	PDGFRA/Fc Protein, Recombinant
PDGFRA/CD140a	Human	PDGFRA Protein, Recombinant
PDGFRA/CD140a	Human	PDGFRA Protein, Recombinant

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human PDGFRA/CD140a	ELISA	Mouse Monoclonal Antibody
Human PDGFRA/CD140a	WB, ELISA	Rabbit Polyclonal Antibody
Human PDGFRA/CD140a	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
PDGF-A	Mouse	Mus musculus PDGF-A cDNA Clone
PDGF-A	Rat	Rat PDGF-A cDNA Clone / ORF Clone
PDGF-B	Human	Homo sapiens PDGF-B cDNA Clone(NM_002608.2)
PDGF-B	Rat	Rattus norvegicus PDGF-B cDNA Clone
PDGF-C	Human	Homo sapiens PDGF-C cDNA Clone(NM_016205.1)
PDGF-D	Human	Homo sapiens PDGF-D transcript variant 1 cDNA Clone(NM_025208.4)
PDGFRA/CD140a	Human	Homo sapiens PDGFRA cDNA Clone(NM_006206.4)

PDGFRB Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level.

PDGFRB Related Studies

1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125–35.
3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
4. Suzuki S, et al. (2010) Clinicopathological significance of platelet-derived growth factor (PDGF)-B and vascular endothelial growth factor-A expression, PDGF receptor-β phosphorylation, and microvessel density in gastric cancer. BMC cancer. 10: 659.