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PDGFRB / CD140b Antibody, Rabbit PAb

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Human PDGFRB Antibody Product Information
Immunogen:Recombinant Human PDGFRb protein (Catalog#10514-H08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human PDGFRb extracellular domain (rh PDGFRb; Catalog#10514-H08H; NP_002600.1; Met 1-Lys 531). Total IgG was purified by Protein A affinity chromatography.
Human PDGFRB Antibody Usage Guide
Specificity:Human PDGFRb / CD140b
Application:ELISA

ELISA: 0.5-1.0 μg/mL

This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human PDGFRB / CD140b. The detection limit for Human PDGFRB / CD140b is 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other PDGFRB Antibody Products
Reactivity: Human  
Application: FCM  
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10514-MM11-P-100
10514-MM11-P-50
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Reactivity: Human  
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10514-R206-P-100
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Reactivity: Human  
Application: ELISA  
    10514-R213-100
    10514-R213-50
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    Reactivity: Human  
    Application: ELISA  
      10514-RP02-50
      10514-RP02-100
      10514-RP02-200
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      Reactivity: Human  
      Application: ELISA  
        10514-MM11-50
        10514-MM11-100
        10514-MM11-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: FCM  
        • Slide 1
        10514-R206-50
        10514-R206-100
        50 µg 
        100 µg 
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        Reactivity: Human  
        Application: FCM  
        • Slide 1
        10514-MM11-F-50
        10514-MM11-F-100
        50 Tests 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: FCM  
        • Slide 1
        10514-R206-F-50
        10514-R206-F-100
        50 Tests 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: IHC-P  
        • Slide 1
        • Slide 1
        10514-MM12-50
        10514-MM12-100
        10514-MM12-200
        50 µg 
        100 µg 
        200 µg 
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        Reactivity: Cynomolgus  
        Application: ELISA  IHC-P  
        • Slide 1
        90215-T24-100
        90215-T24-50
        90215-T24-200
        100 µg 
        50 µg 
        200 µg 
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        Reactivity: Rhesus  
        Application: ELISA  
          90215-RP01-400
          90215-RP01-100
          90215-RP01-200
           
          100 µg 
          200 µg 
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          PDGFRB/CD140b Background

          The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level.

          Human PDGFRB/CD140b References
        • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
        • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
        • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
        • Suzuki S, et al. (2010) Clinicopathological significance of platelet-derived growth factor (PDGF)-B and vascular endothelial growth factor-A expression, PDGF receptor- phosphorylation, and microvessel density in gastric cancer. BMC cancer. 10: 659.
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          Size / Price
          Catalog: 10514-RP01-100
          List Price: 
          Price:      (You Save: )
          Size:
          100 µg
          200 µg
          Quantity:+-
          AvailabilityIn Stock
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          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"