PBK (Protein|Antibody|cDNA Clone|ELISA Kit)

All PBK reagents are produced in house and quality controlled, including 4 PBK Antibody, 1 PBK ELISA, 30 PBK Gene, 1 PBK Lysate, 1 PBK Protein, 2 PBK qPCR. All PBK reagents are ready to use.

Recombinant PBK proteins are expressed by Baculovirus-Insect Cells with fusion tags as C-His.

PBKantibodies are validated with different applications, which are WB, ELISA, ELISA(Det), ELISA(Cap).

PBKcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each PBK of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

PBKELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

PBK Protein (1)

Species

PBK Protein, Human, Recombinant (His Tag)

10729-H08B

Expression host: Baculovirus-Insect Cells

Human PBK/TOPK Protein 9069
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PBK Antibody (4)

Application Clonality
Host

Anti-PBK Antibody

10729-MM10

Application: ELISA(Cap)

Clonality: MAb

Anti-PBK Antibody

10729-RP01

Application: ELISA

Clonality: PAb

Anti-PBK Antibody

10729-MM05

Application: WB,ELISA,ELISA(Det)

Clonality: MAb

Human PBK/TOPK Western blot (WB) 13266

Anti-PBK Antibody

10729-RP02

Application: ELISA

Clonality: PAb

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PBK ELISA KIT & match antibody elias pair set ( 1 )

PBK Matched ELISA Antibody Pair Set,Human

SEK10729

Assay Range: 62.5 pg/ml

Human PBK/TOPK ELISA Pair Set Standard Curve 13864

PBK cDNA Clone (30)

Mouse
Human

PBK qPCR Primer (2)

PBK Lysate (1)

PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the characteristic protein kinase subdomains and a C-terminal PDZ-binding T/SXV motif. PBK is expressed in the testis restrictedly expressed in outer cell layer of seminiferous tubules, as well as placenta. PBK may be enrolled in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.This mitotic kinase phosphorylates MAP kinase p38 and seems to be active in mitosis. When phosphorylated, PBK forms a protein-protein interaction with tumor suppressor p53 (TP53), leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. The expression level of PBK is thus upregulated in a variety of neoplasms including hematological malignancies.

Protein
Antibody
ELISA
Gene
qPCR
Lysate
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