PARK7 / DJ-1 (Protein|Antibody|cDNA Clone|ELISA Kit)

All PARK7 / DJ-1 reagents are produced in house and quality controlled, including 3 PARK7 / DJ-1 Antibody, 47 PARK7 / DJ-1 Gene, 1 PARK7 / DJ-1 IPKit, 1 PARK7 / DJ-1 Protein, 2 PARK7 / DJ-1 qPCR. All PARK7 / DJ-1 reagents are ready to use.

Recombinant PARK7 / DJ-1 proteins are expressed by E. coli with fusion tags as C-His.

PARK7 / DJ-1antibodies are validated with different applications, which are WB, ELISA, IHC-P, FCM, ICC/IF, IF, IP.

PARK7 / DJ-1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each PARK7 / DJ-1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

PARK7 / DJ-1 Protein (1)

Species

PARK7 / DJ-1 Protein, Human, Recombinant (His Tag)

12484-H08E

Expression host: E. coli

Human PARK7/DJ-1 Protein 10074
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PARK7 / DJ-1 Antibody (3)

Application Clonality
Host

Anti-PARK7 / DJ-1 Antibody

12484-T56

Application: WB,ELISA,IHC-P

Clonality: PAb

Human PARK7/DJ-1 Immunohistochemistry(IHC) 3820

Anti-PARK7 / DJ-1 Antibody

12484-RP01

Application: WB

Clonality: PAb

Human PARK7/DJ-1 Western blot (WB) 13499

Anti-PARK7 / DJ-1 Antibody

12484-R007

Application: WB,FCM,ICC/IF,IF,IP

Clonality: MAb

Human PARK7/DJ-1 Immunofluorescence(IF) 2873
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PARK7 / DJ-1 cDNA Clone (47)

Rat
Mouse
Human

PARK7 / DJ-1 qPCR Primer (2)

PARK7 / DJ-1 IP Kit (1)

Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress. PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Mutations in the DJ-1 gene are associated with rare forms of autosomal recessive early-onset Parkinson's disease (PD). DJ-1/p53 interactions contribute to apoptosis resistance in clonal myeloid cells and may serve as a prognostic marker in patients with myelodysplastic syndromes (MDS). DJ-1 regulates redox signaling kinase pathways and acts as a transcriptional regulator of antioxidative gene batteries. Therefore, DJ-1 is an important redox-reactive signaling intermediate controlling oxidative stress after ischemia, upon neuroinflammation, and during age-related neurodegenerative processes. Augmenting DJ-1 activity might provide novel approaches to treating chronic neurodegenerative illnesses such as Parkinson's disease and acute damage such as stroke.

Protein
Antibody
Gene
qPCR
IPKit
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