Osteoprotegerin (Protein|Antibody|cDNA Clone|ELISA Kit)

All Osteoprotegerin reagents are produced in house and quality controlled, including 3 Osteoprotegerin Antibody, 39 Osteoprotegerin Gene, 3 Osteoprotegerin Lysate, 4 Osteoprotegerin Protein, 3 Osteoprotegerin qPCR. All Osteoprotegerin reagents are ready to use.

Recombinant Osteoprotegerin proteins are expressed by HEK293 Cells, Baculovirus-Insect Cells with fusion tags as C-human IgG1-Fc, C-His.

Osteoprotegerin antibodies are validated with different applications, which are ELISA.

Osteoprotegerin cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Osteoprotegerin of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

Osteoprotegerin Protein (4)

Species

Osteoprotegerin Protein, Mouse, Recombinant (Fc Tag)

52613-M02H

Expression host: HEK293 Cells

Mouse Osteoprotegerin/TNFRSF11B Protein 12187

Osteoprotegerin Protein, Human, Recombinant (Fc Tag)

10271-H02B

Expression host: Baculovirus-Insect Cells

Human Osteoprotegerin Protein 20093

Osteoprotegerin Protein, Human, Recombinant (His Tag)

10271-H08H

Expression host: HEK293 Cells

Human Osteoprotegerin/TNFRSF11B Protein 8617

Osteoprotegerin Protein, Rhesus, Recombinant (Fc Tag)

90136-C02H

Expression host: HEK293 Cells

Rhesus Osteoprotegerin/TNFRSF11B Protein 12832
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Osteoprotegerin Antibody (3)

Application
Clonality
Host

Anti-Osteoprotegerin Antibody

10271-R340

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-Osteoprotegerin Antibody

10271-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-Osteoprotegerin Antibody

10271-T16

Specificity: Human

Application: ELISA

Clonality: PAb

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Osteoprotegerin cDNA Clone (39)

Rat
Human
Mouse

Osteoprotegerin qPCR Primer (3)

Osteoprotegerin Lysate (3)

Osteoprotegerin or TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. Osteoprotegerin/TNFRSF11B acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. This protein may inhibit the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. Osteoprotegerin/TNFRSF11B also play a role in preventing arterial calcification, act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Protein
Antibody
Gene
qPCR
Lysate
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