NOTCH1 (Protein|Antibody|cDNA Clone|ELISA Kit)

All NOTCH1 reagents are produced in house and quality controlled, including 4 NOTCH1 Antibody, 3 NOTCH1 Lysate, 3 NOTCH1 Protein. All NOTCH1 reagents are ready to use.

Recombinant NOTCH1 proteins are expressed by HEK293 Cells, CHO Stable Cells, Baculovirus-Insect Cells with fusion tags as C-human IgG1-Fc, C-His.

NOTCH1 antibodies are validated with different applications, which are ELISA, IHC-P, ICC/IF, IF.

NOTCH1 Protein (3)

Species

NOTCH1 Protein, Mouse, Recombinant (ECD, Fc Tag)

50654-M02S

Expression host: CHO Stable Cells

Mouse NOTCH1 Protein 11804

NOTCH1 Protein, Human, Recombinant (Fc Tag)

10954-H02H

Expression host: HEK293 Cells

Human NOTCH1 Protein 18584

NOTCH1 Protein, Mouse, Recombinant (His Tag)

50654-M08B

Expression host: Baculovirus-Insect Cells

Mouse NOTCH1 Protein 11805
Go

NOTCH1 Antibody (4)

Application Clonality
Host

Anti-NOTCH1 Antibody

50654-T16

Specificity: Mouse

Application: ELISA

Clonality: PAb

Anti-NOTCH1 Antibody

100296-T08

Specificity: Human

Application: IHC-P

Clonality: PAb

Human NOTCH1 Immunohistochemistry(IHC) 3850

Anti-NOTCH1 Antibody

100296-T10

Specificity: Human

Application: IHC-P,ICC/IF,IF

Clonality: PAb

Human NOTCH1 Immunohistochemistry(IHC) 17235

Anti-NOTCH1 Antibody

50654-RP01

Specificity: Mouse

Application: ELISA

Clonality: PAb

Go

NOTCH1 Lysate (3)

NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair regeneration of skeletal muscles.NOTCH1 is a prevalent signaling pathway in T cell acute lymphoblastic leukemia (T-ALL).The NOTCH signaling pathway is a conserved signaling cascade that regulates many aspects of development and homeostasis in multiple organ systems.The proto-oncogene NOTCH1 is frequently mutated in around 1% of patients with chronic lymphocytic leukemia (CLL). NOTCH1 mutations in oral squamous cell carcinoma (OSCC) frequently occur near the ligand-binding region. These mutations change the domain structure of this protein and affect the ligand binding activity. When NOTCH1 is activated by ligand binding, NOTCH1 intracellular domain (NICD) is cleaved from the cell membrane.
Protein
Antibody
Lysate
Close