Neuronal Cell Markers

Protein Name	Alternative Names	BioChemical Class / Role	Products (Cat NO)
			Protein	Antibody	Gene cDNA clones
CD90/THY-1	CDw90, FLJ33325	It is a member of the immunoglobulin superfamily of adhesion molecules with constitutive expression on fibroblast cells. CD90/THY-1 is modulated following infection with Human cytomegalovirus (HCMV). Neuroblastoma (NBL) is the most common solid tumor in children. THY1 / CD90 seemed to be a marker with a specific prognostic value in NBL patients. It may also play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.	50461-M08H		MG50461-M
CD112	Nectin-2, PVRL2	A type I transmembrane glycoprotein belonging to the Ig superfamily. CD112 has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus. CD112 is a potential target for anti-allergic therapy.	10005-H02H 10005-H08H 10005-HCCH 50318-M08H	10005-MM01 10005-RP03 10005-RP04	HG10005-M
CD166	ALCAM	A cell adhesion molecule and a member of the Ig superfamily. CD166/CD6 interaction plays a role in T cell development and regulation, as well as in the binding of T- and B-cells to activated leukocytes. It has also been observed upregulated on highly metastasizing melanoma cell lines, suggesting a role in tumor migration.	50005-M03H 50005-M08H		HG10045-M MG50005-M
L1CAM	CD171, NCAM-L1	A transmembrane cell adhesion molecule belonging to the Ig superfamily, primarily expressed on projection axons of the central nervous system and peripheral nervous system, as well as on a few non-neuronal cell types. L1CAM may play a role in a variety of processes integral to the development of the nervous system, including neuronal migration, neurite outgrowth, and axon fasciculation. L1CAM is also overexpressed in a variety of human carcinomas and is associated with bad prognosis.	10140-H03H		HG10140-M
Latexin	LXN, ECI, TCI	Human Latexin, also known as tissue or endogenous carboxypeptidase inhibitor (TCI or ECI), is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is related to a human putative tumor suppressor protein, TIG1, and Latexin is also implicated in Alzheimer's disease.	10211-H01H 10211-H07E		HG10211-M MG50050-M