Anti-NXPH1 Antibody

Cat: 80047-R021
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Anti-NXPH1 Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-NXPH1 Antibody
Validated applications
Species reactivity
Reacts with: Rat
Recombinant Rat Neurexophilin-1 / NXPH1 protein (Catalog#80047-R08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Rat Neurexophilin-1 / NXPH1 (rR Neurexophilin-1 / NXPH1; Catalog#80047-R08H; Q63366-1; Met1-Gly271).
Monoclonal Rabbit IgG Clone #021
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-NXPH1 Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

NXPH1 Background Information

Neurexophilin-1, or NXPH1 is a secreted glycoprotein, which belongs to the Neurexophilin family. The Neurexophilin family contain at least four genes and resembles a neuropeptide, suggesting a function as an endogenous ligand for alpha-neurexins. The mammalian brains contain four genes for neurexophilins the products of which share a common structure composed of five domains: an N-terminal signal peptide, a variable N-terminal domain, a highly conserved central domain that is N-glycosylated, a short linker region, and a conserved C-terminal domain that is cysteine-rich. Neurexophilin-1 constitutes a secreted cysteine-rich glycoprotein, forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. Neurexophilins 1 and 3 but not 4 (neurexophilin 2 is not expressed in rodents) bind to a single individual LNS domain, the second overall LNS domain in all three alpha-neurexins.

Full Name
neurexophilin 1
  • Missler M, et al. (1998) Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit. J Biol Chem. 273(52): 34716-23.
  • Missler M, et al. (1998) Neurexophilins form a conserved family of neuropeptide-like glycoproteins. J Neurosci. 18(10): 3630-8.
  • Petrenko AG, et al. (1996) Structure and evolution of neurexophilin. J Neurosci. 16(14): 4360-9.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-NXPH1 Antibody Rabbit Monoclonal IHC-P 80047-R001
    Anti-NXPH1 Antibody Rabbit Polyclonal ELISA 80047-T16
    Anti-NXPH1 Antibody Rabbit Polyclonal ELISA 80047-RP01
    Anti-NXPH1 Antibody Rabbit Polyclonal ELISA 50865-T16
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