NRAS cDNA ORF Clone in Cloning Vector, Human

Cat: HG12073-G
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NRAS cDNA ORF Clone in Cloning Vector, Human General Information
Gene
Species
Human
NCBI Ref Seq
RefSeq ORF Size
570 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human neuroblastoma RAS viral (v-ras) oncogene homolog.
Plasmid
Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
NRAS cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

NRAS cDNA ORF Clone in Cloning Vector, Human Alternative Names
ALPS4 cDNA ORF Clone, Human;CMNS cDNA ORF Clone, Human;N-ras cDNA ORF Clone, Human;NCMS cDNA ORF Clone, Human;NRAS1 cDNA ORF Clone, Human;NS6 cDNA ORF Clone, Human
NRAS Background Information

NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL60, a promyelocytic leukemia line. The mammalian ras gene family consists of the harvey and kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1) and the N-ras gene. They differ significantly only in the C-terminal 40 amino acids. These ras genes have GTP/GDP binding and GTPase activity, and their normal function may be as G-like regulatory proteins involved in the normal control of cell growth. The NRAS gene specifies two main transcripts of 2Kb and 4.3Kb. The difference between the two transcripts is a simple extension through the termination site of the 2Kb transcript. The NRAS gene consists of seven exons (-I, I, II, III, IV, V, VI).

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
neuroblastoma RAS viral (v-ras) oncogene homolog
References
  • Marshall CJ. et al., 1982, Nature. 299 (5879): 171-3.
  • Hall Alan. et al., 1983, Nature. 303 (5916): 396-400.
  • McCormick F. 1996, Mol Reprod Dev. 42 (4): 500-6.
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    NRAS cDNA ORF Clone, Human, Related Products

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    NRAS cDNA ORF Clone, Human, untagged HG12073-UT
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    NRAS cDNA ORF Clone, Human, C-His tag HG12073-CH
    NRAS cDNA ORF Clone, Human, N-His tag HG12073-NH
    NRAS cDNA ORF Clone, Human, C-HA tag HG12073-CY
    NRAS cDNA ORF Clone, Human, N-HA tag HG12073-NY
    NRAS cDNA ORF Clone, Human, C-Myc tag HG12073-CM
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