NRAS cDNA ORF Clone in Cloning Vector, Human General Information
Identical with the Gene Bank Ref. ID sequence.
Full length Clone DNA of Human neuroblastoma RAS viral (v-ras) oncogene homolog.
SP6 and T7 or M13-47 and RV-M
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
NRAS cDNA ORF Clone in Cloning Vector, Human Alternative Names
ALPS4 cDNA ORF Clone, Human;CMNS cDNA ORF Clone, Human;N-ras cDNA ORF Clone, Human;NCMS cDNA ORF Clone, Human;NRAS1 cDNA ORF Clone, Human;NS6 cDNA ORF Clone, Human
NRAS Background Information
NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL6, a promyelocytic leukemia line. The mammalian ras gene family consists of the harvey and kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1) and the N-ras gene. They differ significantly only in the C-terminal 4 amino acids. These ras genes have GTP/GDP binding and GTPase activity, and their normal function may be as G-like regulatory proteins involved in the normal control of cell growth. The NRAS gene specifies two main transcripts of 2Kb and 4.3Kb. The difference between the two transcripts is a simple extension through the termination site of the 2Kb transcript. The NRAS gene consists of seven exons (-I, I, II, III, IV, V, VI).Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
neuroblastoma RAS viral (v-ras) oncogene homolog
Marshall CJ. et al., 1982, Nature. 299 (5879): 171-3. Hall Alan. et al., 1983, Nature. 303 (5916): 396-400. McCormick F. 1996, Mol Reprod Dev. 42 (4): 500-6.