NGF Protein & Antibody (Nerve growth factor, NGFB, beta-NGF)

Nerve growth factor (beta polypeptide)

NGF Products

NGF Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
NGF/NGFB	Human	NGF Protein, Recombinant	11050-HNAC
NGF/NGFB	Mouse	NGF Protein, Recombinant	50385-MNAC

 11050-HNAC:

1. The ED₅₀ for this effect is typically 0.4-1.0 ng / ml  Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.

2. The ED₅₀ for this effect is typically 1.07 ng / ml. Measured in a cell survival assay using PC-12 rat pheochromocytoma cells.

NGF Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human NGF/NGFB	WB, ELISA	NGF/NGFB Antibody, Rabbit PAb	11050-RP01
Human NGF/NGFB	WB, ELISA	NGF / NGFB Antibody, Rabbit PAb(Antigen Affinity Purified)	11050-RP02

NGF cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
NGF/NGFB	Human	Homo sapiens NGF cDNA Clone(NM_002506.2)	HG11050-C
NGF/NGFB	Mouse	Mus musculus NGF cDNA Clone	MG50385-M
NGF/NGFB	Canine	Canine NGF Gene cDNA Clone / ORF Clone	DG70027-G
NGF/NGFB	Rat	Rat NGF Gene cDNA Clone / ORF Clone	RG80426-G
NGF/NGFB	Rat	Rat NGF ORF Expression Clone, FLAG-tagged	RG80426-G-F
NGF/NGFB	Rat	Rat NGF ORF Expression Clone, His-tagged	RG80426-G-H
NGF/NGFB	Rat	Rat NGF ORF Expression Clone, untagged	RG80426-G-N

NGF Alternative Names

NGF, NGFB, Beta-NGF, HSAN5, MGC161426, MGC161428

NGF Related Areas

Neuroscience>>Neurotrophic Factor & Receptor>>Neurotrophin & Receptor>>NGF

Cancer>>Growth Factor & Receptor>>Neurotrophin & Receptor>>NGF

NGF Protein Related Products

Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
BDNF	Mouse	BDNF Protein, Recombinant, with Native
NGFR	Mouse	NGFR / P75 Protein, Recombinant
NGFR	Mouse	NGFR / P75 Protein, Recombinant
NGFR	Human	NGFR/ P75 Protein, Recombinant
NGFR	Human	NGFR / P75 Protein, Recombinant
TrkA/NTRK1	Human	TrkA/NTRK1/Fc Protein, Recombinant
TrkA/NTRK1	Human	TrkA/NTRK1 Protein (aa 194-413), Recombinant
TrkA/NTRK1	Human	TrkA/NTRK1 Protein (aa 285-413), Recombinant
TrkA/NTRK1	Human	TrkA/NTRK1 Protein, Recombinant
TrkB/NTRK2	Human	TrkB/NTRK2/Fc Protein, Recombinant
TrkB/NTRK2	Human	TrkB/NTRK2 Protein, Recombinant
TrkB/NTRK2	Mouse	TrkB/NTRK2 Protein, Recombinant
TrkC/NTRK3	Human	TrkC/NTRK3/Fc Protein, Recombinant
TrkC/NTRK3	Human	TrkC/NTRK3 Protein, Recombinant
TrkC/NTRK3	Mouse	TrkC/NTRK3 Protein, Recombinant

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human TrkA/NTRK1	WB, ELISA	Mouse Monoclonal Antibody
Human TrkA/NTRK1	WB, ELISA	Mouse Monoclonal Antibody
Human TrkA/NTRK1	WB, ELISA	TrkA/NTRK1 Antibody, Rabbit MAb
Human TrkA/NTRK1	IHC-P	TrkA / NTRK1 Antibody
Human TrkA/NTRK1	WB, ELISA	Rabbit Polyclonal Antibody
Human TrkA/NTRK1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human TrkB/NTRK2	WB	Mouse Monoclonal Antibody
Human TrkB/NTRK2	WB, ELISA, IHC	TrkB/NTRK2 Antibody, Rabbit MAb
Human TrkB/NTRK2	WB, ELISA	Rabbit Polyclonal Antibody
Human TrkB/NTRK2	WB, ELISA, IHC	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human TrkC/NTRK3	WB, ELISA	Mouse Monoclonal Antibody
Human TrkC/NTRK3	WB, ELISA	Rabbit Monoclonal Antibody
Human TrkC/NTRK3	WB, ELISA	Rabbit Polyclonal Antibody
Human TrkC/NTRK3	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse TrkC/NTRK3	WB, ELISA	TrkC/NTRK3 Antibody, Rabbit PAb
Mouse TrkC/NTRK3	WB, ELISA	TrkC/NTRK3 Antibody, Rabbit PAb (Antigen Affinity Purified)

ELISA Kit Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human TrkA/NTRK1	ELISA	TrkA/NTRK1 ELISA Kit

cDNA Clone Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
BDNF	Human	Human BDNF transcript variant 4 Gene cDNA Clone / ORF Clone
BDNF	Mouse	Mouse BDNF Gene cDNA Clone / ORF Clone
BDNF	Canine	Canine BDNF Gene cDNA Clone / ORF Clone
NT-3	Human	Human NT-3 transcript variant2 Gene cDNA Clone / ORF Clone
NT-4	Human	Human NT-4 Gene cDNA Clone / ORF Clone
NT-4	Mouse	Mouse NT-4 Gene cDNA Clone / ORF Clone
NGFR	Human	Human NGFR cDNA Clone / ORF Clone
NGFR	Mouse	Mouse NGFR cDNA Clone / ORF Clone
NGFR	Canine	Canine NGFR / TNFRSF16 Gene cDNA Clone / ORF Clone
TrkA/NTRK1	Human	Homo sapiens TrkA/NTRK1 cDNA Clone
TrkA/NTRK1	Mouse	Mouse NTRK1 Gene cDNA Clone / ORF Clone
TrkA/NTRK1	Rat	NTRK1 cDNA Clone / ORF Clone
TrkB/NTRK2	Human	Homo sapiens TrkB/NTRK2 transcript variant b cDNA Clone(NM_001007097.1)
TrkB/NTRK2	Mouse	Mus musculus TrkB/NTRK2 cDNA Clone
TrkB/NTRK2	Canine	Canine NTRK2 Gene cDNA Clone / ORF Clone
TrkB/NTRK2	Rat	Rat NTRK2 cDNA Clone / ORF Clone
TrkC/NTRK3	Human	Homo sapiens TrkC/NTRK3 transcript variant 3 cDNA Clone(NM_001007156.1)
TrkC/NTRK3	Mouse	Mus musculus TrkC/NTRK3 cDNA Clone

NGF Background

Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

NGF Related Studies

1. Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
2. Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
3. Xanthos DN, et al. (2009) The roles of nerve growth factor and cholecystokinin in the enhancement of morphine analgesia in a rodent model of central nervous system inflammation. Neuropharmacology. 56(3): 684-91.
4. Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.