Merlin / NF2 cDNA ORF Clone in Cloning Vector, Human


Merlin / NF2 cDNA ORF Clone in Cloning Vector, Human: General Information

NCBI Ref Seq
RefSeq ORF Size
1524 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Full length Clone DNA of Human neurofibromin 2 (merlin).
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.

Merlin / NF2 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Merlin / NF2 cDNA ORF Clone in Cloning Vector, Human: Alternative Names

ACN cDNA ORF Clone, Human; BANF cDNA ORF Clone, Human; merlin cDNA ORF Clone, Human; SCH cDNA ORF Clone, Human

Merlin / NF2 Background Information

NF2 (neurofibromin 2) is an established tumor suppressor that promotes apoptosis and inhibits growth in a variety of cell types.The NF2 gene product Merlin is a FERM-domain protein possessing a broad tumor-suppressing function. NF2/Merlin has been implicated in regulating multiple signaling pathways critical for cell growth and survival.The NF2 gene is a putative tumor-suppressor gene that, when it is altered in the germline, causes neurofibromatosis type 2, a tumor-susceptibility disease that mainly predisposes to schwannomas and meningiomas.Loss of function mutations or deletions in NF2 cause neurofibromatosis type 2 (NF2), a multiple tumor forming disease of the nervous system. NF2 is characterized by the development of bilateral vestibular schwannomas.NF2 gene alterations may have a clinical impact in non-NF2 vestibular schwannomas (VSs).
Full Name
neurofibromin 2 (merlin)
Add to Cart Successfully Add to Cart Failed Shopping cart is being updated, please wait