All NKp30 reagents are produced in house and quality controlled, including 4 NKp30 Antibody, 4 NKp30 Gene, 4 NKp30 Lysate, 4 NKp30 Protein, 1 NKp30 qPCR. All NKp30 reagents are ready to use.
Recombinant NKp30 proteins are expressed by HEK293 Cells with fusion tags as C-His, C-human IgG1-Fc & His.
NKp30antibodies are validated with different applications, which are WB, ELISA.
NKp30cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each NKp30 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity, and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.