Anti-ARD1A Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human NAA10 / ARD1A protein (Catalog#14293-H20B)
Produced in rabbits immunized with purified, recombinant Human NAA10 / ARD1A (rh NAA10 / ARD1A; Catalog#14293-H20B; P41227; Met1-Ser235). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-ARD1A Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-ARD1A Antibody Alternative Names
Anti-ARD1 Antibody;Anti-ARD1A Antibody;Anti-ARD1P Antibody;Anti-DXS707 Antibody;Anti-MCOPS1 Antibody;Anti-NAA10 Antibody;Anti-NATD Antibody;Anti-OGDNS Antibody;Anti-TE2 Antibody
ARD1A Background Information
ARD1 is a member of the 20-kDa ARF protein family. It is a multifunctional protein. ARD1 has an 18-kDa ADP-ribosylation factor (ARF) domain at the C-terminus (amino acids 403-574), and a 46-kDa N-terminal domain (amino acids 1-402). The C-terminal region of ARD1 may be involved in the formation of both ARD1-ARD1 and ARD1-NAT1 complexes. ARD1 and NAT1 genes are required for the expression of an N-terminal protein acetyltransferase. This activity is required for full repression of the silent mating type locus HML, for sporulation, and for entry into G0. Recombinant ARD1 (amino acids 1-574) or its RING finger domain (amino acids 1-110) produced polyubiquitylated proteins when incubated in vitro with a mammalian E1, an E2 enzyme, ATP, and ubiquitin.
N(alpha)-acetyltransferase 10, NatA catalytic subunit
Tribioli C., et al.,(1994), Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae. Hum. Mol. Genet. 3:1061-1068.Arnesen T., et al., (2005), Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.Biochem. J. 386:433-443.Ross M.T., et al.,(2005), The DNA sequence of the human X chromosome.Nature 434:325-337.