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N-Cadherin / CD325 / CDH2 Antibody 
| Catalog | Size (Price) | Quantity | In Stock | Operation | Other Information |
| 11039-R014 |
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YES | 
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N-Cadherin / CD325 / CDH2 Antibody Datasheet
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Order or Inquire for N-Cadherin / CD325 / CDH2 Antibody product | Quality antibodies | Antibody production services | |
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Detection limit is 0.00245ng/well in ELISA |
N-Cadherin / CD325 / CDH2 Antibody Product Information
| Immunogen : |
Recombinant Human N-Cadherin / CD325 / CDH2 protein (Catalog#11039-H08H) |
| Antibody Type : | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
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Clone ID : |
014 |
| Ig Type : |
Rabbit IgG |
| Formulation : | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation : |
This antibody was obtained from a rabbit immunized with purified, recombinant Human N-Cadherin / CD325 / CDH2 (rh N-Cadherin / CD325 / CDH2; Catalog#11039-H08H; NP_001783.2; Met 1-Ala 724). |
N-Cadherin / CD325 / CDH2 Antibody Usage Guide
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Specificity : |
Human N-Cadherin / CD325 / CDH2 |
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| Immunochemistry : |
ICC/IF: 5-15 μg/mL
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| Western blot : | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human CDH2 in WB. | ||
| Direct ELISA : | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CDH2. The detection limit for Human CDH2 is approximately 0.00245 ng/well. | ||
| Storage : | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
N-Cadherin / CD325 / CDH2 Antibody Related Products & Topics
Related Areas:
Neuroscience>>Synaptic Protein>>N-Cadherin/CDH2/CD325
Stem Cell>>Mesenchymal Stem Cell (MSC)>>Mesenchymal Stem Cell Marker>>N-Cadherin/CDH2/CD325
Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>N-Cadherin/CDH2/CD325
Immunology>>Adhesion Molecule>> Cadherin>>N-Cadherin/CDH2/CD325
Immunology>>Cluster of Differentiation>>N-Cadherin/CDH2/CD325
Proteins:
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| N-Cadherin/CD325/CDH2 | Human | N-Cadherin/CD325/CDH2 Protein, Recombinant | 11039-H08H |
Antibodies:
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human N-Cadherin/CD325/CDH2 | FCM | N-Cadherin / CD325 / CDH2 Antibody | 11039-R001 |
| Human N-Cadherin/CD325/CDH2 | WB, ELISA | N-Cadherin / CD325 / CDH2 Antibody | 11039-R014 |
| Human N-Cadherin/CD325/CDH2 | WB, ELISA | N-Cadherin / CD325 / CDH2 Antibody | 11039-R017 |
| Human N-Cadherin/CD325/CDH2 | WB, ELISA, FCM | N-Cadherin / CD325 / CDH2 Antibody | 11039-R020 |
N-Cadherin / CD325 / CDH2 Antibody Background
Cadherins are calcium dependent cell adhesion proteins, and they preferentially interact with themselves in a homophilic manner in connecting cells. Human cadherin 2, type 1, N-cadherin (neuronal) (NCAD), also known as CDH2, is a single-pass tranmembrane protein and a cadherin containing 5 cadherin domains. N-cadherin displays a ubiquitous expression pattern but with different expression levels between endocrine cell types. CDH2 (NCAD) has been shown to play an essential role in normal neuronal development, which is implicated in an array of processes including neuronal differentiation and migration, and axon growth and fasciculation. In addition, N-cadherin expression was upregulated in human HSC during activation in culture, and function or expression blocking of N-cadherin promoted apoptosis. During apoptosis, N-cadherin was cleaved into 20-100 kDa fragments. N-cadherin cleavage occurred at a higher level in glioblastoma cells than in non-neoplastic astrocytes.
References
- LaMora A. et al., 2009, Neuroscience. 159: 1175-1184.
- Chauvet N. et al., 2009, J Endocrinol. 202: 375-387.
- Hartland S.N. et al., 2009, Liver Int. 29: 966-978.
- Kohutek Z.A. et al., 2009, J Neurosci. 29: 4605-4615.
N-Cadherin/CD325/CDH2 related areas, pathways, and other information
