TFPI qPCR Primer Pairs, Mouse

Cat: MP200161
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TFPI qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
TFPI qPCR Primer Pairs, Mouse Alternative Names
A630013F22Rik qPCR Primer Pairs, Mouse;AW552122 qPCR Primer Pairs, Mouse;EPI qPCR Primer Pairs, Mouse;LACI qPCR Primer Pairs, Mouse
TFPI Background Information

Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. With its Kunitz domains, TFPI exhibits significant homology with human inter-alpha-trypson inhibitor and bovin basic pancreatic trypsin inhibitor. TFPI is the natural inhibitor of TF coagulant and signaling activities. The importance of TFPI in the regulation of blood coagulation is emphasized by how its activity is modulated in human disease. In a factor (F) Xa-dependent feedback system, TFPI binds directly and inhibits the TF-FVII/FVIIa complex. Normally, TFPI exists in plasma both as a full-length molecule and as variably carboxy-terminal truncated forms. TFPI also circulates in complex with plasma lipoproteins. The levels and the dual inhibitor effect of TFPI on FXa and TF-FVII/FVIIa complex offers insight into the mechanisms of various pathological conditions triggered by TF. TFPI may play an important role in modulating TF-induced thrombogenesis and it may also provide a unique therapeutic approach for prophylaxis and/or treatment of various diseases. In addition, Studies have shown that TFPI exhibits antiangiogenic and antimetastatic effects in vitro and in vivo. In animal models of experimental metastasis, both circulating and tumor cell-associated TFPI are shown to significantly reduce tumor cell-induced coagulation activation and lung metastasis.

Full Name
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
References
  • Lwaleed BA, et al. (2006) Tissue factor pathway inhibitor: structure, biology and involvement in disease. J Pathol. 208(3): 327-39.
  • Amirkhosravi A, et al. (2007) The role of tissue factor pathway inhibitor in tumor growth and metastasis. Semin Thromb Hemost. 33(7): 643-52.
  • Maroney SA, et al. (2008) Expression of tissue factor pathway inhibitor by endothelial cells and platelets. Transfus Apher Sci. 38(1): 9-14.
  • TFPI qPCR Primer Pairs, Rat, Related Products

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    TFPI qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    TFPI cDNA ORF Clone in Cloning Vector, Mouse MG50131-M
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    TFPI Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50131-ACGLN
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    TFPI cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50131-CF
    TFPI cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50131-NF
    TFPI cDNA ORF Clone, Mouse, C-His tag MG50131-CH
    TFPI cDNA ORF Clone, Mouse, N-His tag MG50131-NH
    TFPI cDNA ORF Clone, Mouse, C-HA tag MG50131-CY
    TFPI cDNA ORF Clone, Mouse, N-HA tag MG50131-NY
    TFPI cDNA ORF Clone, Mouse, C-Myc tag MG50131-CM
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    TFPI qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    TFPI cDNA ORF Clone in Cloning Vector, Human HG10564-M
    TFPI cDNA ORF Clone, Human, untagged HG10564-UT
    TFPI Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10564-ACGLN
    TFPI cDNA ORF Clone, Human, C-GFPSpark® tag HG10564-ACG
    TFPI cDNA ORF Clone, Human, C-OFPSpark® tag HG10564-ACR
    TFPI cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10564-CF
    TFPI cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10564-NF
    TFPI cDNA ORF Clone, Human, C-His tag HG10564-CH
    TFPI cDNA ORF Clone, Human, N-His tag HG10564-NH
    TFPI cDNA ORF Clone, Human, C-HA tag HG10564-CY
    TFPI cDNA ORF Clone, Human, N-HA tag HG10564-NY
    TFPI cDNA ORF Clone, Human, C-Myc tag HG10564-CM
    TFPI cDNA ORF Clone, Human, N-Myc tag HG10564-NM
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