Nogo Receptor qPCR Primer Pairs, Mouse

Cat: MP200136
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Nogo Receptor qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Nogo Receptor qPCR Primer Pairs, Mouse Alternative Names
NgR qPCR Primer Pairs, Mouse;NgR1 qPCR Primer Pairs, Mouse;NOGOR qPCR Primer Pairs, Mouse;Rtn4r qPCR Primer Pairs, Mouse
Nogo Receptor Background Information

Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 10 LRP (Leucine-rich) repeats. RTN4R is expressed predominantly in neurons and their axons in the central nervous systems (CNS). As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG), and myelin oligodendrocyte glycoprotein (OMG), RTN4R mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. It has been shown that RTN4R performs its inhibitory actions by interacting with the p75 neurotrophin receptor (p75NTR), a TNFRSF member also known for modulating the activities of the Trk family and for inducing apoptosis in neurons and oligodendrocytes. RTN4R may be proposed as a potential drug target for treatment of various neurological conditions such as spinal cord injury, CNS lesions, peripheral nerve injury, stroke and Alzheimer's disease (AD). Additionally, RTN4R may play a role in regulating the function of the gap junctions.

Full Name
reticulon 4 receptor
References

1. Wang, X. et al., 2006, Ann Neurol. 60(5): 540-549.      

2. Wang, Y.Z. et al., 2006, Neuroreport.17(6):605-609.       

3. Zhu, H.Y. et al., 2007, Hum Pathol. 38(3): 426-434.           

4. David, S. et al., 2008, Trends Neurosci. 31(5): 221-226.       

5. Jiang, W. et al., 2009, Transl Res. 154(1): 40-48.      

6. Zhang, L. et al., 2009, J Neurosci, 9(19): 6348-6352.

Nogo Receptor qPCR Primer Pairs, Mouse, Related Products

Product Name Catalog#(PDF)
Nogo Receptor cDNA ORF Clone in Cloning Vector, Mouse MG50106-M
Nogo Receptor cDNA ORF Clone, Mouse, untagged MG50106-UT
Nogo Receptor cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50106-ACG
Nogo Receptor Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50106-ACGLN
Nogo Receptor cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50106-ACR
Nogo Receptor cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50106-CF
Nogo Receptor cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50106-NF
Nogo Receptor cDNA ORF Clone, Mouse, C-His tag MG50106-CH
Nogo Receptor cDNA ORF Clone, Mouse, N-His tag MG50106-NH
Nogo Receptor cDNA ORF Clone, Mouse, C-HA tag MG50106-CY
Nogo Receptor cDNA ORF Clone, Mouse, N-HA tag MG50106-NY
Nogo Receptor cDNA ORF Clone, Mouse, C-Myc tag MG50106-CM
Nogo Receptor cDNA ORF Clone, Mouse, N-Myc tag MG50106-NM

Nogo Receptor qPCR Primer Pairs, Human, Related Products

Product Name Catalog#(PDF)
Nogo Receptor cDNA ORF Clone in Cloning Vector, Human HG10466-M
Nogo Receptor cDNA ORF Clone, Human, untagged HG10466-UT
Nogo Receptor Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10466-ACGLN
Nogo Receptor cDNA ORF Clone, Human, C-GFPSpark® tag HG10466-ACG
Nogo Receptor cDNA ORF Clone, Human, C-OFPSpark® tag HG10466-ACR
Nogo Receptor cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10466-CF
Nogo Receptor cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10466-NF
Nogo Receptor cDNA ORF Clone, Human, C-His tag HG10466-CH
Nogo Receptor cDNA ORF Clone, Human, N-His tag HG10466-NH
Nogo Receptor cDNA ORF Clone, Human, C-HA tag HG10466-CY
Nogo Receptor cDNA ORF Clone, Human, N-HA tag HG10466-NY
Nogo Receptor cDNA ORF Clone, Human, C-Myc tag HG10466-CM
Nogo Receptor cDNA ORF Clone, Human, N-Myc tag HG10466-NM
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