PD-1 qPCR Primer Pairs, Mouse

Cat: MP200154
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All PD-1 Reagents
CRO Services
Product recommended

All PD-1 Reagents
PD-1 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
NCBI RefSeq:
PCR Size:
176bp
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
PD-1 qPCR Primer Pairs, Mouse Alternative Names
Ly101 qPCR Primer Pairs, Mouse;PD-1 qPCR Primer Pairs, Mouse;Pdc1 qPCR Primer Pairs, Mouse
PD-1 Background Information

Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyrosine phosphatase, SHP-2 upon interacting with either of two ligands, PD-L1 or PD-L2. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. Furthermore, PD1 is shown to be a regulator of virus-specific CD8+ T cell survival in HIV infection. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.

Immune Checkpoint
Immune Checkpoint Blockade: Blocking Antibodies   Immune Checkpoint Blockade: PD1 / PDCD1 / CD279 Blocking Antibodies
Immune Checkpoint Detection: Antibodies   Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins   PD1 / PDCD1 / CD279 Immune Checkpoint Proteins
PD1 / PDCD1 / CD279 Immune Checkpoint   PD1 / PDCD1 / CD279 Immune Checkpoint Antibodies
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
programmed cell death 1
References
  • James ES, et al. (2005) PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders. Genes Immun. 6(5): 430-7.
  • Okazaki T, et al. (2007) PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol. 19(7): 813-24.
  • del Rio ML, et al. (2008) PD-1/PD-L1, PD-1/PD-L2, and other co-inhibitory signaling pathways in transplantation. Transpl Int. 21(11): 1015-28.
  • Riley JL.(2009) PD-1 signaling in primary T cells. Immunol Rev. 229(1): 114-25.
  • PD-1 qPCR Primer Pairs, Canine, Related Products

    Product Name Catalog#(PDF)
    PD-1 cDNA ORF Clone in Cloning Vector, Canine DG70109-G
    PD-1 cDNA ORF Clone, Canine, untagged DG70109-UT
    PD-1 Lentiviral cDNA ORF Clone, Canine, C-GFPSpark® tag DG70109-ACGLN
    PD-1 cDNA ORF Clone, Canine, C-GFPSpark® tag DG70109-ACG
    PD-1 cDNA ORF Clone, Canine, C-OFPSpark® tag DG70109-ACR
    PD-1 cDNA ORF Clone, Canine, C-DDK (Flag®) tag DG70109-CF
    PD-1 cDNA ORF Clone, Canine, N-DDK (Flag®) tag DG70109-NF
    PD-1 cDNA ORF Clone, Canine, C-His tag DG70109-CH
    PD-1 cDNA ORF Clone, Canine, N-His tag DG70109-NH
    PD-1 cDNA ORF Clone, Canine, C-HA tag DG70109-CY
    PD-1 cDNA ORF Clone, Canine, N-HA tag DG70109-NY
    PD-1 cDNA ORF Clone, Canine, C-Myc tag DG70109-CM
    PD-1 cDNA ORF Clone, Canine, N-Myc tag DG70109-NM

    PD-1 qPCR Primer Pairs, Rhesus, Related Products

    Product Name Catalog#(PDF)
    PD-1 cDNA ORF Clone in Cloning Vector, Rhesus KG90305-G
    PD-1 cDNA ORF Clone, Rhesus, untagged KG90305-UT
    PD-1 Lentiviral cDNA ORF Clone, Rhesus, C-GFPSpark® tag KG90305-ACGLN
    PD-1 cDNA ORF Clone, Rhesus, C-GFPSpark® tag KG90305-ACG
    PD-1 cDNA ORF Clone, Rhesus, C-OFPSpark® tag KG90305-ACR
    PD-1 cDNA ORF Clone, Rhesus, C-DDK (Flag®) tag KG90305-CF
    PD-1 cDNA ORF Clone, Rhesus, N-DDK (Flag®) tag KG90305-NF
    PD-1 cDNA ORF Clone, Rhesus, C-His tag KG90305-CH
    PD-1 cDNA ORF Clone, Rhesus, N-His tag KG90305-NH
    PD-1 cDNA ORF Clone, Rhesus, C-HA tag KG90305-CY
    PD-1 cDNA ORF Clone, Rhesus, N-HA tag KG90305-NY
    PD-1 cDNA ORF Clone, Rhesus, C-Myc tag KG90305-CM
    PD-1 cDNA ORF Clone, Rhesus, N-Myc tag KG90305-NM

    PD-1 qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    PD-1 cDNA ORF Clone in Cloning Vector, Rat RG80448-G
    PD-1 cDNA ORF Clone, Rat, untagged RG80448-UT
    PD-1 cDNA ORF Clone, Rat, C-GFPSpark® tag RG80448-ACG
    PD-1 Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80448-ACGLN
    PD-1 cDNA ORF Clone, Rat, C-OFPSpark® tag RG80448-ACR
    PD-1 cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80448-CF
    PD-1 cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80448-NF
    PD-1 cDNA ORF Clone, Rat, C-His tag RG80448-CH
    PD-1 cDNA ORF Clone, Rat, N-His tag RG80448-NH
    PD-1 cDNA ORF Clone, Rat, C-HA tag RG80448-CY
    PD-1 cDNA ORF Clone, Rat, N-HA tag RG80448-NY
    PD-1 cDNA ORF Clone, Rat, C-Myc tag RG80448-CM
    PD-1 cDNA ORF Clone, Rat, N-Myc tag RG80448-NM

    PD-1 qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    PD-1 cDNA ORF Clone in Cloning Vector, Mouse MG50124-M
    PD-1 cDNA ORF Clone, Mouse, untagged MG50124-UT
    PD-1 Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50124-ACGLN
    PD-1 cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50124-ACG
    PD-1 cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50124-ACR
    PD-1 cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50124-CF
    PD-1 cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50124-NF
    PD-1 cDNA ORF Clone, Mouse, C-His tag MG50124-CH
    PD-1 cDNA ORF Clone, Mouse, N-His tag MG50124-NH
    PD-1 cDNA ORF Clone, Mouse, C-HA tag MG50124-CY
    PD-1 cDNA ORF Clone, Mouse, N-HA tag MG50124-NY
    PD-1 cDNA ORF Clone, Mouse, C-Myc tag MG50124-CM
    PD-1 cDNA ORF Clone, Mouse, N-Myc tag MG50124-NM

    PD-1 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    PD-1 cDNA ORF Clone in Cloning Vector, Human HG10377-M
    PD-1 cDNA ORF Clone, Human, untagged HG10377-UT
    PD-1 cDNA ORF Clone, Human, C-GFPSpark® tag HG10377-ACG
    PD-1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10377-ACGLN
    PD-1 cDNA ORF Clone, Human, C-OFPSpark® tag HG10377-ACR
    PD-1 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10377-CF
    PD-1 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10377-NF
    PD-1 cDNA ORF Clone, Human, C-His tag HG10377-CH
    PD-1 cDNA ORF Clone, Human, N-His tag HG10377-NH
    PD-1 cDNA ORF Clone, Human, C-HA tag HG10377-CY
    PD-1 cDNA ORF Clone, Human, N-HA tag HG10377-NY
    PD-1 cDNA ORF Clone, Human, C-Myc tag HG10377-CM
    PD-1 cDNA ORF Clone, Human, N-Myc tag HG10377-NM
    info info
    添加购物车成功! 添加购物车失败!