Latexin qPCR Primer Pairs, Mouse

Cat: MP200050
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Latexin qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
Latexin Background Information

Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI and LXN, is a cytoplasm protein which belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional specification of the neocortex in development in rats. The 222 amino acid latexin in human shows different expression distribution with high levels in heart, prostate, ovary, kidney, pancreas, and colon, but only moderate or low levels in other tissues including brain. Latexin is also expressed at high levels and is inducible in macrophages in concert with other protease inhibitors and potential protease targets, and thus is suggested to play a role in inflammation and innate immunity pathways. Despite of the non-detectable sequence similarity with plant and parasite inhibitors, Latexin is related to a human putative tumor suppressor protein, TIG1. In addition, Latexin is also implicated in Alzheimer's disease.

Full Name
latexin
References
  • Liu Q., et al.,(2000), Cloning, tissue expression pattern and genomic organization of latexin, a human homologue of rat carboxypeptidase A inhibitor. Mol. Biol. Rep. 27:241-246.
  • Gauci S., et al., (2009), Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.nal. Chem. 81:4493-4501.
  • Muzny D.M., et al.,(2006), The DNA sequence, annotation and analysis of human chromosome 3.Nature 440:1194-1198.
  • Latexin qPCR Primer Pairs, Mouse, Related Products

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    Latexin qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
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    Latexin cDNA ORF Clone, Human, C-GFPSpark® tag HG10211-ACG
    Latexin cDNA ORF Clone, Human, N-GFPSpark® tag HG10211-ANG
    Latexin cDNA ORF Clone, Human, C-OFPSpark® tag HG10211-ACR
    Latexin cDNA ORF Clone, Human, N-OFPSpark® tag HG10211-ANR
    Latexin cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10211-CF
    Latexin cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10211-NF
    Latexin cDNA ORF Clone, Human, C-His tag HG10211-CH
    Latexin cDNA ORF Clone, Human, N-His tag HG10211-NH
    Latexin cDNA ORF Clone, Human, C-HA tag HG10211-CY
    Latexin cDNA ORF Clone, Human, N-HA tag HG10211-NY
    Latexin cDNA ORF Clone, Human, C-Myc tag HG10211-CM
    Latexin cDNA ORF Clone, Human, N-Myc tag HG10211-NM
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