LIFR qPCR Primer Pairs, Mouse

Cat: MP200088
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LIFR qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
LIFR qPCR Primer Pairs, Mouse Alternative Names
A230075M04Rik qPCR Primer Pairs, Mouse;AW061234 qPCR Primer Pairs, Mouse;LIF qPCR Primer Pairs, Mouse
LIFR Background Information

LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus affects the differentiation, proliferation, and survival of a wide variety of cells in the adult and the embryo. Besides LIF, LIFR can also bind to and activate CNTF (ciliary neurotrophic factor) and CLC (cardiotrophin like cytokine). Evidence showed that in the retina, LIFR activating LIF, CT-1 and cardiotrophin like cytokine (CLC) are strongly upregulated in response to preconditioning with bright cyclic light leading to robust activation of signal transducer and activator of transcription-3 (STAT3) in a time-dependent manner. Further, blocking LIFR activation during preconditioning using a LIFR antagonist (LIF05) attenuated the induced STAT3 activation and also resulted in reduced preconditioning-induced protection of the retinal photoreceptors. These data demonstrate that LIFR and its ligands play an essential role in endogenous neuroprotective mechanisms triggered by preconditioning-induced stress. LIFR was newly found to be a suppressor of hepatocellular carcinoma (HCC), one of the world's top five causes of cancer-related deaths.

Full Name
leukemia inhibitory factor receptor alpha
References
  • Gearing, D.P. et al.,1991, EMBO J. 10 (10): 2839-2848.
  • Gearing, D.P. et al.,1992, New Biol. 4 (1): 61-65.
  • Mosley, B. et al.,1996, J. Biol. Chem. 271 (51): 32635-32643.
  • Timmermann, A. et al.,2002, Eur. J. Biochem. 269 (11): 2716-2726.
  • Lass, A. et al.,2002, Fertil. Steril. 76 (6): 1091-1096.
  • LIFR qPCR Primer Pairs, Rhesus, Related Products

    Product Name Catalog#(PDF)
    LIFR cDNA ORF Clone in Cloning Vector, Rhesus CG90210-G
    LIFR cDNA ORF Clone, Rhesus, untagged CG90210-UT
    LIFR cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90210-ACG
    LIFR Lentiviral cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90210-ACGLN
    LIFR cDNA ORF Clone, Rhesus, C-OFPSpark® tag CG90210-ACR
    LIFR cDNA ORF Clone, Rhesus, C-DDK (Flag®) tag CG90210-CF
    LIFR cDNA ORF Clone, Rhesus, N-DDK (Flag®) tag CG90210-NF
    LIFR cDNA ORF Clone, Rhesus, C-His tag CG90210-CH
    LIFR cDNA ORF Clone, Rhesus, N-His tag CG90210-NH
    LIFR cDNA ORF Clone, Rhesus, C-HA tag CG90210-CY
    LIFR cDNA ORF Clone, Rhesus, N-HA tag CG90210-NY
    LIFR cDNA ORF Clone, Rhesus, C-Myc tag CG90210-CM
    LIFR cDNA ORF Clone, Rhesus, N-Myc tag CG90210-NM

    LIFR qPCR Primer Pairs, Rat, Related Products

    Product Name Catalog#(PDF)
    LIFR cDNA ORF Clone in Cloning Vector, Rat RG80322-G
    LIFR cDNA ORF Clone, Rat, untagged RG80322-UT
    LIFR cDNA ORF Clone, Rat, C-GFPSpark® tag RG80322-ACG
    LIFR Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG80322-ACGLN
    LIFR cDNA ORF Clone, Rat, C-OFPSpark® tag RG80322-ACR
    LIFR cDNA ORF Clone, Rat, C-DDK (Flag®) tag RG80322-CF
    LIFR cDNA ORF Clone, Rat, N-DDK (Flag®) tag RG80322-NF
    LIFR cDNA ORF Clone, Rat, C-His tag RG80322-CH
    LIFR cDNA ORF Clone, Rat, N-His tag RG80322-NH
    LIFR cDNA ORF Clone, Rat, C-HA tag RG80322-CY
    LIFR cDNA ORF Clone, Rat, N-HA tag RG80322-NY
    LIFR cDNA ORF Clone, Rat, C-Myc tag RG80322-CM
    LIFR cDNA ORF Clone, Rat, N-Myc tag RG80322-NM

    LIFR qPCR Primer Pairs, Mouse, Related Products

    Product Name Catalog#(PDF)
    LIFR cDNA ORF Clone in Cloning Vector, Mouse MG50423-M
    LIFR cDNA ORF Clone, Mouse, untagged MG50423-UT
    LIFR cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50423-ACG
    LIFR Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50423-ACGLN
    LIFR cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50423-ACR
    LIFR cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50423-CF
    LIFR cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50423-NF
    LIFR cDNA ORF Clone, Mouse, C-His tag MG50423-CH
    LIFR cDNA ORF Clone, Mouse, N-His tag MG50423-NH
    LIFR cDNA ORF Clone, Mouse, C-HA tag MG50423-CY
    LIFR cDNA ORF Clone, Mouse, N-HA tag MG50423-NY
    LIFR cDNA ORF Clone, Mouse, C-Myc tag MG50423-CM
    LIFR cDNA ORF Clone, Mouse, N-Myc tag MG50423-NM

    LIFR qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
    LIFR cDNA ORF Clone in Cloning Vector, Human HG10628-M
    LIFR cDNA ORF Clone, Human, untagged HG10628-UT
    LIFR Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10628-ACGLN
    LIFR cDNA ORF Clone, Human, C-GFPSpark® tag HG10628-ACG
    LIFR cDNA ORF Clone, Human, C-OFPSpark® tag HG10628-ACR
    LIFR cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10628-CF
    LIFR cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10628-NF
    LIFR cDNA ORF Clone, Human, C-His tag HG10628-CH
    LIFR cDNA ORF Clone, Human, N-His tag HG10628-NH
    LIFR cDNA ORF Clone, Human, C-HA tag HG10628-CY
    LIFR cDNA ORF Clone, Human, N-HA tag HG10628-NY
    LIFR cDNA ORF Clone, Human, C-Myc tag HG10628-CM
    LIFR cDNA ORF Clone, Human, N-Myc tag HG10628-NM
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