JAM2 qPCR Primer Pairs, Mouse

Cat: MP200092
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JAM2 qPCR Primer Pairs, Mouse General Information
Target Details
Species:
Mouse
Product Details
Oligo-Type:
qPCR Primers
Component:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCR Primer Description:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
Application & Quality
Application:
SYBR® Green-based quantitative real-time PCR (qPCR).
Quality Control:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
Storage & Shipping
Shipping:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
Storage:
The lyophilized product is stable for one year from date of receipt when stored at -20℃. The suspended product is stable for six months from date of receipt when stored at -20℃.

***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***

Features and Advantages
Unique Primer Design
To avoid genomic DNA amplification, at least one primer is designed crosses the junction of exons according to the conserved region of a specific gene with all variants.
Strict Validation Process
Confirmed in positive organizations; screened the primer with high specificity and high sensitivity.
Uniform PCR conditions, Saving time and cost
~100% amplification curve, ensuring the accuracy of the RNA quantitative
JAM2 qPCR Primer Pairs, Mouse Alternative Names
1110002N23Rik qPCR Primer Pairs, Mouse;2410030G21Rik qPCR Primer Pairs, Mouse;2410167M24Rik qPCR Primer Pairs, Mouse;JAM-2 qPCR Primer Pairs, Mouse;JAM-B qPCR Primer Pairs, Mouse;Jcam2 qPCR Primer Pairs, Mouse;VE-JAM qPCR Primer Pairs, Mouse
JAM2 Background Information

Junctional adhesion molecule B (JAM-B), also known as Junctional adhesion molecule 2 (JAM2), Vascular endothelial junction-associated molecule (VE-JAM), and CD322, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. It is prominently expressed on high endothelial venules. expression to be restricted to the high endothelial venule of tonsil and lymph nodes. The localization to the endothelium of arterioles in and around inflammatory and tumor foci. JAM-B can function as an adhesive ligand for the T cell line J45 and can interact with GM-CSF/IL-4-derived peripheral blood dendritic cells, circulating CD56(+) NK cells, circulating CD56(+)CD3(+) NK/T cells, and circulating CD56(+)CD3(+)CD8(+) cytolytic T cells. JAM-2 is expressed on high endothelial venules (HEVs) in human tonsil and on a subset of human leukocytes, suggesting that JAM-2 plays a central role in the regulation of transendothelial migration. It binds to very late activation antigen (VLA)-4, a leucocyte integrin that contributes to rolling and firm adhesion of lymphocytes to endothelial cells through binding to vascular cell adhesion molecule (VCAM)-1. JAM-B appears to contribute to leucocyte extravasation by facilitating not only transmigration but also rolling and adhesion. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Full Name
junctional adhesion molecule 2
References
  • Johnson-Lger CA, et al. (2002) Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration. Blood. 2100(7): 2479-86.
  • Liang TW, et al. (2002) Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3. J Immunol. 168(4): 1618-26.
  • Ludwig RJ, et al. (2009) Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin. Immunology. 128(2): 196-205.
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    JAM2 qPCR Primer Pairs, Mouse, Related Products

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    JAM2 qPCR Primer Pairs, Human, Related Products

    Product Name Catalog#(PDF)
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    JAM2 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10580-ACGLN
    JAM2 cDNA ORF Clone, Human, C-OFPSpark® tag HG10580-ACR
    JAM2 cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10580-CF
    JAM2 cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10580-NF
    JAM2 cDNA ORF Clone, Human, C-His tag HG10580-CH
    JAM2 cDNA ORF Clone, Human, N-His tag HG10580-NH
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    JAM2 cDNA ORF Clone, Human, N-HA tag HG10580-NY
    JAM2 cDNA ORF Clone, Human, C-Myc tag HG10580-CM
    JAM2 cDNA ORF Clone, Human, N-Myc tag HG10580-NM
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